- 1. B Double Prime
- [Encoded by human PR48 Gene (PP2A Regulatory Subunit B Family), 414-aa nuclear Protein Phosphatase 2A 48kDa Regulatory Subunit is a B regulatory subunit of PP2A. PR48 specifically interacts with the N-terminal region of and dephosphorylates CDC6, modulating initiation of DNA replication and cell cycle control. A major heterotrimeric Ser/Thr phosphatase implicated in negative control of many cellular processes including cell growth and division, PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B regulatory subunit or with cell signaling molecules, that likely modulate substrate selectivity, catalytic activity, and subcellular localization, yielding the trimeric holoenzyme. Combinations of different subunit isoforms can generate many forms of PP2A that may differ in substrate specificity, subcellular location, or tissue specific expression. (NCI) ( NCI )] (UMLS (NCI) C1335537) NY-REN-8;
NY-REN-8 Antigen;
PP2A B Double Prime Subunit PR48;
PP2A Subunit B PR48 Isoform;
PR48;
Protein Phosphatase-2A-48kDa Regulatory Subunit;
Serine/Threonine Protein Phosphatase 2A 48kDa Regulatory Subunit;
Serine/Threonine Protein Phosphatase 2A 48kDa Regulatory Subunit B =Amino Acid, Peptide, or Protein; Enzyme ;
| - 3. B-Double Prime 1 Subunit of RNA Polymerase III Transcription Initiation Factor IIIB
- [Encoded by widely expressed human BDP1 Gene, 2254-aa 253-kD highly hydrophilic Transcription Factor-Like Nuclear Regulator contains several potential phosphorylation sites, two bipartite NLS, a DNA-ligase A1 ATP-dependent binding site, a MYB-like domain, and 9 copies of a 55-amino acid motif. Similar to yeast TFC5 and required for RNA polymerase III transcription, BDP1 binds promoter regions, suggesting that it is part of the initiation complex. (NCI) ( NCI )] (UMLS (NCI) C0966598) BDP1;
hB-Double Prime;
HSA238520;
KIAA1241;
KIAA1689;
Putative Transcription Factor-Like Nuclear Regulator;
Putative Transcription Regulation Nuclear Protein;
RNA Polymerase III GTF3B Subunit 1;
TAF3B1;
TATA Box Binding Protein (TBP)-Associated Factor;
TFC5;
TFIIIB150;
TFIIIB90;
TFNR;
Transcription Factor-Like Nuclear Regulator =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
home
