- 1. B-DNA
- [A duplex of DNA is formed by two complementary chains that are arranged in an anti-parallel manner. B-DNA is about 20 Angstrom in diameter and a right-handed double helix with a wide major groove easily accessible to proteins and narrow minor groove. B-DNA is the most common DNA conformation in vivo and the favored conformation at high water concentrations. Base pairs are nearly perpendicular to the helix axis and sugar pucker is C2'-endo. ( NCI )] (UMLS (NCI) C0919262) B-Form DNA;
Right-Handed DNA =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
| - 3. BDNF
- [This gene is involved in neuron differentiation, proliferation and survival. ( NCI )] (UMLS (NCI) C1332408) BDNF Gene;
Brain-Derived Neurotrophic Factor Gene;
=Gene or Genome ;
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- 2. BDNF
- [member of the neurotrophin family of peptide growth factors. ( CSP )] (UMLS (NCI) C0107103) =Amino Acid, Peptide, or Protein; Biologically Active Substance =Neurotrophic Factor;
| - 4. BDNF/NT-3 Growth Factors Receptor
- [Widely expressed (mainly neural tissue) by human NTRK2 Gene (IR Tyr Kinase Family) as alternative isoforms TRKB (822-aa 92-kDa precursor), TRKB-T1 (477-aa), and TRKB-T-SHC (537-aa), Neurotrophic Tyrosine Kinase Receptor Type 2 is a type I membrane receptor for BDNF, NTF3, and NTF4/5, but not NGF, involved in development and/or maintenance of the nervous system that contains 2 LRR repeats and 2 Ig-like C2-type domains. Monomeric (low affinity) and dimeric (high affinity) forms appear to exist in dynamic equilibrium. Known substrates for TRK receptors are SHC, PI-3 kinase, and PLC-gamma-1. NTRK2 undergoes ligand-mediated auto-phosphorylation. (NCI) ( NCI )] (UMLS (NCI) C0084873) =Amino Acid, Peptide, or Protein; Enzyme; Receptor
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