BD-1
[Encoded by human DEFB1 Gene (Beta-Defensin Family), Beta-Defensin 1 Protein prepropeptide contains a 68-amino acid secreted antimicrobial plasma peptide implicated in cystic fibrosis pathogenesis. Multiple plasma forms are bound to carrier macromolecules. Highest DEFB1 concentrations occur in kidney and female reproductive tract epithelia. DEFB1 may act in innate immunity. Mammalian alpha- and beta-defensins comprise 3.5- to 5-kD cysteine- and arginine-rich neutrophilic microbicidal and cytotoxic peptides. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C0625647- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor
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