[Encoded by human BRF1 Gene (TFIIB Family), alternative isoforms 1 (677-aa, 74-kD), 2 (134-aa, altered N- and C-termini), 3 (473-aa, shorter N-terminus), and 4 (242-aa) of General Transcription Factor 3B 90-kD Subunit function at different promoters on tRNA, 5S rRNA, and other small RNA genes. Related to GTF2B (N-terminus), GTF3B contains a highly charged region and HMG2-related region. Essential for transcription initiation, GTF3B (C-terminus) binds TBP (collectively, TFIIIB) as one of three RNA polymerase III transcription factor subunits. Following GTF3A or GTF3C recognition of promoter elements, GTF3B and RNA polymerase III bind sequentially. (NCI) ( NCI )]
UMLS (NCI) C1096984BRF
BRF1
BRF1 Homolog
BRF1 Homolog Subunit of RNA Polymerase III Transcription Initiation Factor IIIB
BRF1, S. cerevisiae, Homolog of
BRF1: BRF1 Homolog, Subunit of RNA Polymerase III Transcription Initiation Factor IIIB (S.cerevisiae)
General Transcription Factor 3B 90-kD Subunit
General Transcription Factor 3B, 90-kD Subunit
General Transcription Factor IIIB 90kD Subunit
GTF3B
GTF3B 90-kD Subunit
GTF3B, 90-kD Subunit
hBRF
TAF3B2
TAF3C
TAFIII90
TATA Box Binding Protein (TBP)-Associated Factor 3C
TATA Box Binding Protein (TBP)-Associated Factor RNA Polymerase III Subunit 2
TATA Box-Binding Protein-Associated Factor RNA Polymerase III Subunit 2
TATA Box-Binding Protein-Associated Factor, RNA Polymerase III, Subunit 2
TBP-Associated Factor RNA Polymerase III 90kD
TBP-Associated Factor, RNA Polymerase III, 90-kD
TF3B90
TFIIIB90
Transcription Factor IIIB 90-kD Subunit
Transcription Factor IIIB, 90-kD Subunit
Transcription Initiation Factor IIIB
- Amino Acid, Peptide, or Protein
- Biologically Active Substance