- 1. BR96-DOX
- [An antibody-drug conjugate composed of the chimeric monoclonal antibody BR96 chemically linked to the cytotoxic drug doxorubicin. The antibody moiety of BMS-182248-1 binds to Lewis Y, a cell surface antigen expressed on many solid tumor types. Thus, the doxorubicin conjugate is targeted specifically to Lewis Y-expressing tumor cells, where it intercalates with DNA, thereby inhibiting DNA replication and repair, RNA synthesis and protein synthesis. (NCI) ( NCI )] (UMLS (NCI) C0295525) =Organic Chemical; Pharmacologic Substance; Immunologic Factor
| - 3. BRD2
- [This gene plays a role in signal transduction and regulation of transcription. It is involved in brain development and spermatogenesis. ( NCI )] (UMLS (NCI) C1366556) BRD2 Gene;
Bromodomain Containing 2 Gene =Gene or Genome |