UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AM AMA AMB AMC AMD AME AMF AMG AMH AMI AML AMM AMN AMO AMP AMS AMT AMV AMY

AMLODIPINE

[A synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreases myocardial contractility, increases blood flow and oxygen delivery to the myocardial tissue and decreases total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump. ( NCI )]
UMLS (NCI) C0051696
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: antihypertensive agent
[CV200] CALCIUM CHANNEL BLOCKERS
Dihydropyridines
[CV250] ANTIANGINALS
Relation/CHD: AMLODIPINE BESYLATE

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