[A synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth. ( NCI )]
UMLS (NCI) C0076110 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: [AM700] ANTIFUNGALS
naphthalene
[DE102] ANTIFUNGAL, TOPICAL
Relation/CHD: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine Hydrochloride