[An alkyl nitrosoguanidine with carcinogenic properties. Used to induce cancer in experimental animal models, N-ethyl-N'-nitro-N-nitrosoguanidine ethylates DNA, resulting in single- and double-stranded DNA breaks and the inhibition of DNA replication. (NCI04) ( NCI )] (UMLS (NCI) C0059360) =Organic Chemical; Hazardous or Poisonous Substance ;