[A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding. ( NCI )] (UMLS (NCI) C0251504) =Organic Chemical; Pharmacologic Substance ; =Acetamides; Pyrimidine; [CN309] SEDATIVES/HYPNOTICS, OTHER; =ZALEPLON 10 MG; ZALEPLON 5 MG;