- 1. RG 12915
- [A 5-hydroxytryptamine-3 (5-HT3) receptor antagonist with antiemetic activity. RG 12915 binds to and antagonizes the action of serotonin on 5-HT-3 receptor located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. ( NCI )] (UMLS (NCI) C0246228) =Organic Chemical; Pharmacologic Substance ;
| - 3. RG 14620
- [A non-phenolic tyrphostin-class tyrosine kinase inhibitor that inhibits epidermal growth factor receptor, affecting cell proliferation and tumor growth in vivo. (NCI) ( NCI )] (UMLS (NCI) C0378953) =Organic Chemical; Pharmacologic Substance
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