[Encoded by human PSIP1 Gene, Transcriptional Coactivator p75 is an alternatively spliced product that shares a 325-aa region with Transcriptional Coactivator p52, but shows distinct coactivator properties. p75 interacts strongly with the VP16 activation domain. p52 is a potent broad-specificity coactivator; p75 is less active for most activation domains. (NCI) ( NCI )] (UMLS (NCI) C0761475) PAIP; PC4 and SFRS1 Interacting Protein 1; PC4 and SFRS1 Interacting Protein 2; PSIP1; PSIP2; Transcriptional Coactivator p75; =Amino Acid, Peptide, or Protein; Biologically Active Substance ;