- 1. 1-0-Octadecyl-2-O-methyl-Sn-3-glycero-phosphocholine Liposome
- [A liposomal formulation of the ether lipid 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine with potential antineoplastic activity. TLC ELL-12 induces tumor cell apoptosis via mitochondria- and caspase-mediated mechanisms. Liposomal encapsulation reduces the free agent's hemolytic toxicity. (NCI04) ( NCI )] (UMLS (NCI) C1313443) ELL-12;
TLC ELL-12 =Organic Chemical; Pharmacologic Substance ;
| - 7. Octreoscan
- (UMLS (NCI) C0753746) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
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- 2. 1-Octadecyl-2-methoxy-rac-glycero-3-phosphocholine
- [A synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for edelfosine has not been fully elucidated. Targeting cellular membranes, edelfosine modulates membrane permeability, membrane lipid composition, and phospholipid metabolism. Edelfosine also inhibits the phosphatidylinositol 3 kinase (PI3K)-AKT/PKB survival pathway, possibly activating the pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. In addition, this agent inhibits protein kinase C, intracellular activation of the Fas/CD95 receptor, and intracellular acidification. Anti-leishmanial activity may be due to inhibition of a glycosomal alkyl-specific-acylCoA acyltransferase. (NCI) ( NCI )] (UMLS (NCI) C0044549) =Lipid; Pharmacologic Substance ;
| - 8. Octreotide pamoate
- [A synthetic long-acting octapeptide analogue of endogenous somatostatin. Octreotide pamoate binds to somatostatin receptors expressed by some neuroendocrine and non-neuroendocrine tumor cells, thereby initiating somatostatin receptor-mediated apoptosis. Other possible antineoplastic activities of this agent include suppression of tumor angiogenesis and tumor growth-promoting insulin-like growth factor 1 (IGF-1). (NCI04) ( NCI )] (UMLS (NCI) C0338271) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
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- 3. OCTACAINE
- (UMLS (NCI) C0771989) =Organic Chemical; Pharmacologic Substance ;
| - 9. Octreotide Pamoate/Tamoxifen
- (UMLS (NCI) C0392936) =Therapeutic or Preventive Procedure ;
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- 4. Octastatin
- (UMLS (NCI) C0285417) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 10. Octreotide/Prednisone
- (UMLS (NCI) C0678024) =Therapeutic or Preventive Procedure ;
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- 5. octopamine
- [alpha-adrenergic sympathomimetic catecholamine formed from tyramine and found in the nervous system and in platelets. ( CSP )] (UMLS (CSP) C0028403) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =adrenergic agent;
Neurotransmitter;
phenolic amine;
| - 11. Octreotide/Tamoxifen
- (UMLS (NCI) C0279440) =Therapeutic or Preventive Procedure
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- 6. Octopus
- [An eight-armed cephalopod mollusk belonging to the order Octopoda. It includes the octopus as food. ( MSH )] (UMLS (CSP) C0028831) =Invertebrate
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