- 1. 1-Nitrobenzo[a]pyrene trans-7,8-Dihydrodiol
- (UMLS (NCI) C0768962) =Organic Chemical
| - 34. nitro compound
- [compound containing the chemical group N02. ( CSP )] (UMLS (CSP) C0028138) =Organic Chemical ;
=nitrogen oxide; Organic Chemical =glyceryl trinitrate; Mirbane Oil; nitrophenol; nitroalkane; Nitrobenzenes; nitrofuran; Nitroimidazoles; Nitroquinolines |
- 2. 1-Nitropyrene
- [A synthetic, light sensitive, yellow crystalline solid that is practically insoluble in water and soluble in diethyl ether, acetone, ethanol, benzene and toluene. It is not used for any commercial applications and is used only for research purposes, principally as a marker for exposure to nitro-polycyclic aromatic hydrocarbons from diesel exhaust. When heated to decomposition, 1-nitropyrene emits toxic fumes of nitrogen oxides. This compound is found in particulate emissions from combustion products, of which diesel exhaust is the principle source. The primary route of potential human exposure to 1-nitropyrene is inhalation. This compound is one of the most abundant mononitroarenes detected in ambient air. Occupational exposure to 1-nitropyrene occurs primarily in workers exposed to diesel engine exhaust in the transport industry. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0044508) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 35. nitroalkane
- [any alkane that contains the nitro (NO2) group. ( CSP )] (UMLS (CSP) C0597070) =Organic Chemical ;
=alkane; nitro compound |
- 3. 1-Nitrosopiperidine
- [A clear, yellow, oily, liquid that is light sensitive and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosopiperidine is used in laboratory research to induce tumors in experimental animals. This substance is naturally formed in foods that contain sodium nitrite as a preservative, including meat, fish and cheese, as a result of nitrosation of piperidine in the presence of nitrite. N-Nitrosopiperidine is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068235) =Organic Chemical; Hazardous or Poisonous Substance
| - 36. nitroalkene
- [ ] (UMLS (CSP) C0597788) =Organic Chemical ;
|
- 4. 1-Nitrosopyrrolidine
- [A clear, yellow, oily, liquid nitrosamine that decomposes when exposed to light and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosopyrrolidine is used in laboratory research to induce tumors in experimental animals. This substance may be formed during cooking of foods that contain sodium nitrite as a preservative, including meat, fish and cheese. Exposure to N- Nitrosopyrrolidine irritates the skin and eyes and can damage the liver and kidneys. This substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0027253) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 37. Nitrocarbol
- [A colorless, oily, highly flammable liquid with a strong, disagreeable odor that emits toxic fumes of nitrogen oxides upon decomposition. Nitromethane is used to make industrial antimicrobials and pharmaceuticals, and is also used as a soil fumigant and as a fuel in race car engines. Exposure to nitromethane irritates the skin and affects the central nervous system causing nausea, dizziness and narcosis. This substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068849) =Organic Chemical; Hazardous or Poisonous Substance
|
- 5. 2,2'-(Nitrosoimino)bisethanol
- [A pale yellow, oily liquid nitrosamine with a characteristic odor that is light sensitive and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosodi-n-butylamine is primarily used in laboratory research to induce tumors in experimental animals, but is also used as an intermediate in the synthesis of di-n-butylhydrazine. This substance is detected in various foods, including smoked meats, cheese and soybean oil, as a result of nitrosation of amines that are present in these products and is detected as a contaminant in rubber products. Exposure to N-Nitrosodi-n-butylamine irritates the skin and eyes and may damage the liver and kidneys. This substance is mutagenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068206) =Organic Chemical; Hazardous or Poisonous Substance
| - 38. nitroferricyanide
- [powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function, also used as an indicator for free sulfhydryl groups in proteins. ( CSP )] (UMLS (CSP) C0028193) =Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid; Inorganic Chemical =Ferricyanides;
ferrocyanide =SODIUM NITROPRUSSIDE; |
- 6. 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) Acetamide
- (UMLS (NCI) C0382334) =Organic Chemical; Pharmacologic Substance ;
| - 39. nitrofuran
- [ ] (UMLS (CSP) C0028155) =Organic Chemical; Pharmacologic Substance =Furans;
nitro compound =FURAZOLIDONE; NITROFURANTOIN; nitrofurazone; |
- 7. 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide
- [A nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis. (NCI) ( NCI )] (UMLS (NCI) C0053230) =Organic Chemical; Pharmacologic Substance ;
| - 40. NITROFURANTOIN
- [A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04) ( NCI )] (UMLS (NCI) C0028156) =Organic Chemical; Pharmacologic Substance =nitrofuran;
[AM600] NITROFURANS ANTIMICROBIALS =NITROFURANTOIN MACROCRYSTALLINE; NITROFURANTOIN 25 MG/5ML; NITROFURANTOIN 50 MG; NITROFURANTOIN 100 MG |
- 8. 2-Nitropropane
- [A synthetic, flammable, colorless liquid that is slightly soluble in water, and miscible with most aromatic hydrocarbons, ketones, esters, ethers and the lower carboxylic acids. It is used primarily both as a chemical intermediate and as a solvent for numerous commercial products. 2-Nitropropane is also used as a component of explosives and propellants, and in fuels for internal combustion engines. The primary routes of potential human exposure to 2-nitropropane are dermal contact, inhalation, and ingestion. Contact with this compound can cause irritation of the eyes and skin. Acute inhalation exposure to low levels of 2-nitropropane vapors can result in irritation of the respiratory tract. Breathing higher levels of this chemical may cause anorexia, nausea, vomiting and diarrhea. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0046453) =Organic Chemical; Hazardous or Poisonous Substance
| - 41. NITROFURANTOIN SODIUM
- (UMLS (NCI) C0304331) =Pharmacologic Substance ;
|
- 9. 3-Nitrobenzo[a]pyrene trans-7,8-Dihydrodiol
- (UMLS (NCI) C0768964) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 42. nitrofurazone
- [A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS. ( MSH )] (UMLS (CSP) C0028157) =Organic Chemical; Pharmacologic Substance =nitrofuran;
[DE101] ANTIBACTERIAL, TOPICAL =NITROFURAZONE 0.2 %; |
- 10. 4 nitroquinoline N oxide
- [A potent mutagen and carcinogen. This compound and its metabolite 4-hydroxyaminoquinoline-1-oxide bind to nucleic acids. It inactivates bacteria but not bacteriophage. (MeSH) ( NCI )] (UMLS (CSP) C0000511) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 43. nitrogen
- [Keep in liquid nitrogen ( HL7V3.0 )] (UMLS (HL7) C1550581) =Human-caused Phenomenon or Process =EntityHandling;
|
- 11. 4-(Nitrooxy)butyl 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetate
- (UMLS (NCI) C0381496) =Organic Chemical; Pharmacologic Substance ;
| - 44. nitrogen balance
- [state of body in regard to ingestion and excretion of nitrogen; difference between nitrogen intake and total nitrogen excretion. ( CSP )] (UMLS (CSP) C0429631) =Finding =nitrogen metabolism;
|
- 12. 4-Nitroestrone
- [A synthetic derivative of estradiol. 4-nitroestrone 3-methyl ether inhibits estrogen sulfotransferase (EST), a progesterone-induced secretory endometrial enzyme which affects estrogen receptor levels. This agent has been shown to be an effective growth inhibitor of some chemically induced animal mammary tumors. (NCI04) ( NCI )] (UMLS (NCI) C0048573) =Steroid; Pharmacologic Substance ;
| - 45. nitrogen compound
- [tree heading for selected nitrogen-containing chemicals, including inorganic; for additional organic, see RTs listed here. ( CSP )] (UMLS (CSP) C0684298) =Chemical Viewed Structurally =Chemical;
=ammonia; azo compound; cyanate; cyanide; N element; nitrogen oxide; nitrene |
- 13. 4-Nitropyrene
- [A synthetic, orange needle-shaped solid that is that is practically insoluble in water and soluble in diethyl ether, acetone, ethanol, benzene and toluene. It is not used for any commercial applications and is used only for research purposes. When heated to decomposition, 4-nitropyrene emits toxic fumes of nitrogen oxides. 4-Nitropyrene is found in particulate emissions from combustion products, of which diesel exhaust is the principle source. The primary route of potential human exposure to 4-nitropyrene is inhalation. Low concentrations of 6-nitrochrysene have been found in ambient airborne particulates. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0048629) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 46. Nitrogen Dioxide
- [Found in the atmosphere as a key ingredient in photochemical formation of smog and acid rain, Nitrogen Dioxide is a poisonous gas that forms during combustion. Toxic at high concentrations, it reacts with moisture in the air to form nitric acid, highly corrosive and hazardous to plants and animals. (NCI04) ( NCI )] (UMLS (NCI) C0028160) =Hazardous or Poisonous Substance; Inorganic Chemical ;
|
- 14. 4-Nitrosomorpholine
- [A yellow, crystalline nitrosamine that is sensitive to light. N-Nitrosomorpholine is not used or produced commercially in the US. This substance has been found as a contaminant in rubber products, including rubber nipples for baby bottles, and is also found in several vegetables, cheeses, alcoholic beverages and fruits. N-Nitrosomorpholine is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068232) =Organic Chemical; Hazardous or Poisonous Substance
| - 47. nitrogen dioxide radical
- [ ] (UMLS (CSP) C0598460) =Inorganic Chemical
|
- 15. 9-Nitro-20 (S-)Camptothecin
- [A semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells; this agent also prevents repair of reversible single-strand DNA breaks. (NCI04) ( NCI )] (UMLS (NCI) C0213799) =Organic Chemical; Pharmacologic Substance ;
| - 48. nitrogen fixation
- [ability of certain bacteria, fungi and blue-green algae to convert free atmospheric nitrogen to biologically usable forms such as ammonia, nitrates, or amino groups. ( CSP )] (UMLS (CSP) C0028161) =Organism Function =nitrogen metabolism;
|
- 16. Nitisinone
- (UMLS (NCI) C0173083) =Organic Chemical; Pharmacologic Substance ;
=[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER; Unclassified Ingredients =NITISINONE 2 MG; NITISINONE 5 MG; NITISINONE 10 MG | - 49. nitrogen metabolism
- [sum of chemical changes that occur within the tissues of an organism consisting of anabolism (biosynthesis) and catabolism of nitrogen; the buildup and breakdown of nitrogen for utilization by the organism. ( CSP )] (UMLS (CSP) C0597071) =Molecular Function ;
=Intermediary Metabolism; =nitrogen fixation; nitrogen balance |
- 17. Nitracrine
- [Acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis. ( MSH )] (UMLS (NCI) C0028120) =Organic Chemical; Pharmacologic Substance
| - 50. Nitrogen Mustard Compound
- [A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. ( MSH )] (UMLS (NCI) C0028165) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =mustard compound;
=.gamma.-(p-bis(2-chloroethyl)aminophenyl)butyric acid; 17beta-(estra-1,3,5(10)-triene-3,17-diol 3-[bis(2-chloroethyl)carbamate]; Bis(2-chloroethyl)methylamine; 4-[bis(2-chloroethyl)amino]-L-phenylalanine; Phosphoramide Mustards; 5-(bis-(2-Chloroethyl) Amino) Uracil |
- 18. nitrate
- [the anion and oxidizing agent NO3-. ( CSP )] (UMLS (CSP) C0699857) =Inorganic Chemical ;
=nitrogen oxide; =peroxynitrite | - 51. nitrogen narcosis
- [ ] (UMLS (CSP) C0028166) =Injury or Poisoning
|
- 19. nitrate reductase
- [Oxidoreductases that are specific for the reduction of NITRATES. ( MSH )] (UMLS (CSP) C0028123) =Amino Acid, Peptide, or Protein; Enzyme =NAD(P)H oxidoreductase;
miscellaneous oxidoreductase | - 52. nitrogen oxide
- [header term for class of oxides that contain nitrogen. ( CSP )] (UMLS (CSP) C0028167) =Inorganic Chemical =Gas;
Nitrogen Compounds; oxide; nitrogen compound =EDRF; nitrite; nitro compound; nitroso compound; nitrous oxide; oxime; nitrone; nitrate; EDRF; nitrous oxide |
- 20. nitrendipine
- [1,4-dihydro-2,6-dimethyl-4- nitrophenyl-3,5-pyridine carboxyic acid ethylmethyl ester; calcium channel blocker of the nifedipine family. ( CSP )] (UMLS (CSP) C0028127) =Organic Chemical; Pharmacologic Substance =antihypertensive agent;
[CV200] CALCIUM CHANNEL BLOCKERS; pyridine carboxylate; | - 53. nitrogenase
- [an iron-molybdenum protein which catalyzes the reduction ("fixation") of molecular nitrogen to ammonia in many plants and microorganisms, using reduced ferredoxin and ATP. ( CSP )] (UMLS (CSP) C0028174) =Amino Acid, Peptide, or Protein; Enzyme ;
=miscellaneous oxidoreductase; |
- 21. nitrene
- [highly reactive nitrogen radical analogous to the carbenes, believed to be an intermediate in many rearrangement reactions of azides, triazolines, and other nitrogenous groups. ( CSP )] (UMLS (CSP) C0597068) =Inorganic Chemical ;
=nitrogen compound; | - 54. nitrogenous group transferase
- [Enzymes that catalyze the transfer of nitrogenous groups, primarily amino groups, from a donor, generally an amino acid, to an acceptor, usually a 2-oxoacid. EC 2.6. ( MSH )] (UMLS (CSP) C0525002) =Amino Acid, Peptide, or Protein; Enzyme =EC 2;
=aminotransferase |
- 22. Nitrergic Neuron
- [A nerve cell that uses nitric oxide as its neurotransmitter. ( NCI )] (UMLS (NCI) C0949753) =Cell ;
| - 55. nitrogenous heterocyclic compound
- [ring compounds having at least one nitrogen atom in their nuclei. ( CSP )] (UMLS (CSP) C0597072) =Organic Chemical ;
=Heterocyclic Compound; =acridine; azepine; imidazole; 2 benzazine; lactam; oxazine; phenanthridine; phenanthroline; phenazine; PIPERAZINE; pteridine; purine; pyridine; pyrrole; quinazoline; 1 benzazine; quinolizine; thiadiazine; thiazine; triazine; tropane; Aminoethylene; pyrrolidine; quinoxaline; diazine; nucleobase |
- 23. Nitric Acid
- [6N Nitric acid used to preserve urine for heavy metal analysis. ( HL7V3.0 )] (UMLS (HL7) C1556065) =Intellectual Product =MaterialEntityAdditive;
| - 56. nitrone
- [polarized radical (R=)(R'-)N(+)-O(-) which is in equilibrium with a nitroxide RR'N=O. ( CSP )] (UMLS (CSP) C0068853) =Inorganic Chemical ;
=nitrogen oxide; |
- 24. nitric acid
- [A toxic, corrosive, colorless liquid used to make fertilizers, dyes, explosives, and other chemicals. ( NCI )] (UMLS (NCI) C0068808) =Hazardous or Poisonous Substance; Inorganic Chemical =Acids, Noncarboxylic;
Nitrogen Compounds; Additive/Preservative; =Nitrates; | - 57. nitrophenol
- [any organic compound containing one or more hydroxyl groups and nitro groups attached to a benzene ring. ( CSP )] (UMLS (CSP) C0028187) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=nitro compound; phenol =2,4 dinitrophenol; |
- 25. Nitric Oxide Synthase 1 (Neuronal) Gene
- [This gene plays a role in cell-cell signaling, muscle contraction and synaptic transmission. ( NCI )] (UMLS (NCI) C1417759) NOS1;
NOS1 Gene =Gene or Genome | - 58. nitrosamide
- [ ] (UMLS (CSP) C0598974) =Organic Chemical ;
|
- 26. Nitric Oxide Synthase 2A (Inducible, Hepatocytes) Gene
- [This gene is involved in vasodilation and regulation of the bactericidal/tumoricidal actions of macrophages. ( NCI )] (UMLS (NCI) C1417760) NOS2A;
NOS2A Gene =Gene or Genome | - 59. nitrosamine
- [any of a group of N-nitroso derivatives of secondary amines formed by the combining of nitrates with amines; some show carcinogenic activity. ( CSP )] (UMLS (CSP) C0028197) =Organic Chemical; Hazardous or Poisonous Substance ;
=Cancer Causing Agents; nitroso compound =DENA; |
- 27. Nitric Oxide Synthase 2B Gene
- [This gene plays a role in cell immunity/defense. ( NCI )] (UMLS (NCI) C1417761) NOS2B;
NOS2B Gene =Gene or Genome | - 60. nitroso compound
- [compounds containing the radical NO. ( CSP )] (UMLS (CSP) C0028199) =Organic Chemical =nitrogen oxide;
Organic Chemical =nitrosamine; nitrosoguanidine; nitrosourea; |
- 28. Nitric Oxide Synthase 2C Gene
- [This gene is involved in the cell immunity/defense. ( NCI )] (UMLS (NCI) C1417762) NOS2C;
NOS2C Gene =Gene or Genome | - 61. nitrosobenzene
- [ ] (UMLS (CSP) C0068860) =Organic Chemical ;
|
- 29. Nitric Oxide Synthase 3 (Endothelial Cell) Gene
- [This gene plays a role in signal transduction, angiogenesis and platelet aggregation. ( NCI )] (UMLS (NCI) C1328053) NOS3;
NOS3 Gene =Gene or Genome ; | - 62. nitrosoguanidine
- [ ] (UMLS (CSP) C0028203) =Organic Chemical =Guanidines;
nitroso compound =1-Methyl-3-nitro-1-nitrosoguanidine; |
- 30. Nitric Oxide Synthase Inhibitor
- [A class of agents that inhibit nitric oxide synthases (NOS), enzymes which catalyze the production of nitric oxide (NO). The three known NOS isoforms (neuronal, endothelial and inducible) are all dimeric, bi-domain enzymes that contain iron protoporphyrin IX, flavin adenine dinucleotide, mononucleotide, and tetrahydrobiopterin as bound prosthetic groups. (NCI04) ( NCI )] (UMLS (NCI) C1373060) Nitric Oxide Synthase Inhibitors;
Nitric Oxide Synthetase Inhibitor; NOS Inhibitor =Pharmacologic Substance ; =enzyme inhibitor; | - 63. nitrosourea
- [(nye-TRO-so-yoo-REE-ahz) A group of anticancer drugs that can cross the blood-brain barrier. Carmustine and lomustine are nitrosoureas. ( NCI )] (UMLS (CSP) C0028210) =Organic Chemical; Pharmacologic Substance ;
=Alkylating Activity; nitroso compound; CARBAMIDE; =1,3-Bis(2-chloroethyl)-1-nitrosourea; 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea; 1-Methyl-1-nitrosourea; 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose; 1,3-Bis(2-chloroethyl)-1-nitrosourea; 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea; 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose; |
- 31. nitrification
- [oxidation, especially by bacteria, of ammonium salts to nitrites and the further oxidation of nitrites to nitrates. ( CSP )] (UMLS (CSP) C0597069) =Phenomenon or Process ;
=chemical reaction; | - 64. nitrous acid
- [the weak acid HNO. ( CSP )] (UMLS (CSP) C0028214) =Inorganic Chemical =acid;
Acids, Noncarboxylic; nitrite; Nitrogen Compounds =nitrite; |
- 32. nitrite
- [the anion NO2-. ( CSP )] (UMLS (CSP) C0028137) =Chemical Viewed Structurally ;
=anion; nitrogen oxide; nitrous acid; Organic Chemical =nitrous acid; amyl nitrite; Sodium Nitrite; | - 65. nitrous oxide
- [laughing gas; N2O. ( CSP )] (UMLS (CSP) C0028215) =Pharmacologic Substance; Inorganic Chemical =[CN200] ANESTHETICS;
nitrogen oxide; [CN201] ANESTHETICS INHALATION; =NITROUS OXIDE 99 %; NITROUS OXIDE 99.9 % |
- 33. Nitrite
- [A measurement of the nitrite in a urine specimen. ( NCI )] (UMLS (NCI) C0523792) =Laboratory Procedure
| - 66. Nitrumon
- (UMLS (NCI) C0729059) =Organic Chemical; Pharmacologic Substance ;
|