- 1. NF-AT
- [NFAT is a multi-subunit transcription complex that includes homo- or hetero-dimers of FOS and JUN proteins. NFATC, the Dorsal/Rel family cytosolic component of NFAT, is translocated to the nucleus following TCR-induced PKC stimulation and calmodulin-dependent calcineurin-mediated dephosphorylation. Phosphoprotein NFATP, the 'preexisting component' of NFAT present in the unstimulated T-cell cytosol, locates in the nucleus as part of NFAT after activation. ( NCI )] (UMLS (NCI) C0288011) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| |
home 
Armenian-English 
top