- 1. NER
- [Nucleotide Excision Repair (NER) mends DNA regions that contain chemical adducts, such as UV-induced thymine dimers or carcinogenic adducts, which distort the DNA helix and interfere with replication and transcription. NER is targeted to actively transcribed regions of the genome. During NER in eukaryotes, shape irregularities are detected by protein complexes that slide along the DNA molecule and induce cuts on each side of a lesion several nucleotides away. Removal of the damaged 25-30 nucleotide fragment is followed by repair synthesis and ligation. ( NCI )] (UMLS (NCI) C0524550) =Genetic Function
| - 26. nerve stem cell
- [embryonic cell that develops into a neuron. ( CSP )] (UMLS (CSP) C1113654) Neural Stem Cell;
Neural Stem Cells =Cell =nerve cell;
Mother cell |
- 2. NERISOPAM
- (UMLS (NCI) C0526445) =Organic Chemical; Pharmacologic Substance
| - 27. nerve threshold
- [ ] (UMLS (CSP) C0597034) =Organ or Tissue Function ;
=neural function;
=sensory threshold;
|
- 3. NERV ROOT/PLEXUS DIS NEC
- [ ] (UMLS (ICD9CM) C0154739) =Disease or Syndrome
| - 28. Nerve Tissue
- [The tissue that generates and conducts electrical signals in the body. It contains the neurons. ( NCI )] (UMLS (NCI) C0027757) =Tissue ;
|
- 4. NERV ROOT/PLEXUS DIS NOS
- [ ] (UMLS (ICD9CM) C0270890) =Disease or Syndrome
| - 29. NERVE/MUSCULSKEL SYM NEC
- [ ] (UMLS (ICD9CM) C0159036) =Sign or Symptom
|
- 5. nerve
- [any of the cordlike bundles of fibers made up of neurons through which sensory stimuli and motor impulses pass between the brain or other parts of the central nervous system and the eyes, glands, muscles, and other parts of the body; nerves form a network of pathways for conducting information throughout the body. ( CSP )] (UMLS (CSP) C0027740) =Tissue ;
=Body System, Neurologic;
Body Part =cranial nerve;
nerve ending;
efferent nerve;
spinal nerve;
afferent nerve;
| - 30. nerve/myelin protein
- [proteins associated with the myelin sheath or nerve tissue. ( CSP )] (UMLS (CSP) C0178763) =Amino Acid, Peptide, or Protein; Biologically Active Substance =gene product;
=myelin basic protein;
GFAP;
calcineurin;
myelin proteolipid;
GAP 43;
neurofibromatosis type 1 protein;
synaptotagmin;
synapsin;
synaptophysin;
neurofilament protein;
MAG (myelin associated glycoprotein);
CD56;
alpha synuclein;
neuropilin |
- 6. nerve agent
- [ ] (UMLS (CSP) C1113670) =Hazardous or Poisonous Substance
| - 31. Nervous
- [Having to do with nerves or the nervous system, including the brain and the spinal cord. ( NCI )] (UMLS (NCI) C0599851) =Functional Concept
|
- 7. nerve block
- [A procedure in which medicine is injected directly into or around a nerve or into the spine to block pain. ( NCI )] (UMLS (NCI) C0027741) =Therapeutic or Preventive Procedure ;
| - 32. nervous exhaustion
- [ ] (UMLS (CSP) C0598937) =Mental or Behavioral Dysfunction
|
- 8. nerve cell
- [basic cellular units of nervous tissue; each neuron consists of a body, an axon, and dendrites and their purpose is to receive, conduct, and transmit impulses in the nervous system. ( CSP )] (UMLS (NCI) C0027882) =Cell ;
= ;
Body System, Neurologic =Intercalated Neuron;
motoneuron;
cerebellar Purkinje cell;
Rod;
Cone;
pyramidal cell;
Amacrine Cell;
granule cell;
horizontal cell;
Mauthner's neuron;
mossy fiber;
neuron component;
retinal bipolar neuron;
nerve stem cell | - 33. NERVOUS SYST COMPLC NOS
- [ ] (UMLS (ICD9CM) C0235029) =Pathologic Function
|
- 9. nerve decompression
- [relief of pressure on a nerve by surgical removal of constricting fibrous or bony tissue. ( CSP )] (UMLS (CSP) C0196571) =Therapeutic or Preventive Procedure =Neurological Surgery;
| - 34. NERVOUS SYSTEM ANOM NEC
- [ ] (UMLS (ICD9CM) C0477976) =Congenital Abnormality
|
- 10. nerve ending
- [sensory receptors for afferent fibers, neuroeffectors for efferent fibers. ( CSP )] (UMLS (CSP) C0027747) =Cell Component ;
=nerve;
=neuroeffector;
neuroreceptor;
| - 35. NERVOUS SYSTEM ANOM NOS
- [ ] (UMLS (ICD9CM) C0158541) =Congenital Abnormality ;
|
- 11. Nerve Fiber
- [Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the central nervous system. ( MSH )] (UMLS (NCI) C0027749) =Cell Component ;
| - 36. nervous system carcinoma
- [malignant new growth that arises from epithelium, found in the lining of the nervous system, tending to infiltrate into adjacent tissue and spread (metastasize) to distant organs. ( CSP )] (UMLS (CSP) C0597035) =Neoplastic Process ;
=carcinoma;
Neoplasm of Nervous System |
- 12. nerve gas
- [encompass compounds that have the capacity to inactivate the enzyme acetylcholinesterase (AChE); divided into 2 families, the G agents and the V agents; G agents (tabun, sarin, soman cyclosarin) are volatile compounds that pose mainly an inhalation hazard; V agents (VX, VE, VG, VM, V-gas) are persistent and remain on surfaces for long periods, the consistency of V agents is oily, thus mainly pose a contact hazard. ( CSP )] (UMLS (CSP) C0301224) =Organic Chemical; Hazardous or Poisonous Substance =Neurotoxin;
| - 37. nervous system development
- [Human Nervous System Development begins by differentiation of gastrula ectodermal cells into the neural plate, induced by signals from the mesoderm. Further development of this primordium forms the neural crest and neural tube. Neural crest cells become the peripheral nervous system while the neural tube forms the central nervous system. Cells in both structures differentiate into various glial cells and immature neurons that migrate; differentiate axons, dendrites, and synapses; and mature. ( NCI )] (UMLS (CSP) C0598282) =Organ or Tissue Function
|
- 13. nerve growth factor
- [first of a series of neurotrophic factors that were found to influence the growth and differentiation of sympathetic and sensory neurons; comprised of alpha, beta, and gamma subunits; beta subunit is responsible for its growth stimulating activity. ( CSP )] (UMLS (CSP) C0027752) =Amino Acid, Peptide, or Protein; Biologically Active Substance =Neurotrophic Factor;
=ARIA | - 38. nervous system disorder chemotherapy
- [application of the beneficial effects of drugs to control or cure diseases or abnormal states of the nervous system. ( CSP )] (UMLS (CSP) C0597036) =Therapeutic or Preventive Procedure ;
=chemotherapy;
nervous system disorder therapy =brain disorder chemotherapy;
neuromuscular disorder chemotherapy;
sensory disorder chemotherapy;
|
- 14. Nerve Growth Factor Receptor
- [Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) due to its molecular mass and its ability to bind at low affinity not only NGF, but also other neurotrophins, including brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NTF3), and neurotrophin-4/5 (NTF5). NGFR was the first member of the large superfamily of tumor necrosis factor receptors. The identification of this superfamily helped elucidate some of the biologic functions of NGFR, including its ultimate involvement in the nuclear factor kappa-B (NFKB) and apoptosis pathways. As a monomer, NGFR binds NGF with low affinity. Higher affinity binding is achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA (NTRK1), TRKB (NTRK2), and TRKC (NTRK3). (OMIM) ( NCI )] (UMLS (NCI) C0254837) =Amino Acid, Peptide, or Protein; Receptor ;
| - 39. nervous system disorder diagnosis
- [determination of the presence of a disorder(s) of the nervous system or the distinguishing of one disease or condition from another based on symptoms, medical history, risk factors, and clinical tests. ( CSP )] (UMLS (CSP) C0597037) =Diagnostic Procedure ;
=Diagnosed;
=brain disorder diagnosis;
neuromuscular disorder diagnosis;
sensory disorder diagnosis;
|
- 15. Nerve Growth Factor Receptor (TNFR Superfamily, Member 16) Gene
- [This gene is involved in apoptosis, neuronal growth and signaling. ( NCI )] (UMLS (NCI) C1334879) NGFR;
NGFR Gene;
=Gene or Genome ;
| - 40. nervous system disorder epidemiology
- [study of factors determining and influencing the frequency and distribution of nervous system disorders and injuries and their causes in a defined human population. ( CSP )] (UMLS (CSP) C0597038) =Occupation or Discipline ;
=epidemiology;
|
- 16. Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 Gene
- [This gene is involved in cell signaling and apoptosis. ( NCI )] (UMLS (NCI) C1334878) NGFRAP1;
NGFRAP1 Gene;
=Gene or Genome ;
| - 41. nervous system disorder therapy
- [therapies alone or in any combination, such as rehabilitation, exercise, surgeries, alternative medicine or life style changes; coordinate with applicable therapy terms; for drug therapies use NERVOUS SYSTEM DISORDER CHEMOTHERAPY. ( CSP )] (UMLS (CSP) C0872067) =Therapeutic or Preventive Procedure ;
=Therapeutic Interventions;
=TMS;
nervous system disorder chemotherapy;
stroke therapy |
- 17. Nerve Growth Factor Receptor Type 1
- [Human NTRK1 Gene (TKRI/INSR Family) encodes neuronal TRKA-I and non-neural TRKA-II isoforms (similar biological properties) of type I membrane protein Neurotrophic Tyrosine Kinase Receptor Type 1, containing 2 LRR repeats and 2 Ig-like C2-type domains. NTRK1 exists in dynamic equilibrium as low affinity monomers and high affinity dimers with TRKA, TRKB, or TRKC to bind NGF, NTF3, NTF4/5, and BDNF neurotrophins that regulate development and function of the nociceptive and thermoregulatory nervous systems. Ligand stimulation of TRK activates autophosphorylation, SHC, PI-3 kinase, PLC-gamma-1, and ERK1 signaling pathways. NTRK1 defects cause CIPA. Chromosomal rearrangements of NTRK1 fused to TPM3 or to TFG in t(1;3)(q21;q11) are associated with papillary thyroid carcinoma. (NCI) ( NCI )] (UMLS (NCI) C0072482) =Amino Acid, Peptide, or Protein; Enzyme; Receptor
| - 42. Nervous System Finding
- (UMLS (NCI) C0422837) =Finding
|
- 18. Nerve Impulse Transmission
- [Neuronal Transmission is the intercellular propagation or transfer of a signal, from a neuron to a recipient cell, consisting of an electrical current by ion flux via gap junction or diffusion a chemical neurotransmitter across a synaptic or neuromuscular junction. ( NCI )] (UMLS (NCI) C0678903) =Cell Function ;
| - 43. nervous system imaging/visualization
- [ ] (UMLS (CSP) C0920622) =Diagnostic Procedure ;
|
- 19. NERVE INJ NEC AT BIRTH
- [ ] (UMLS (ICD9CM) C0158925) =Injury or Poisoning
| - 44. nervous system infection
- [invasion and growth of microorganisms in the nervous system; may be clinically inapparent or result in local cellular injury. ( CSP )] (UMLS (CSP) C0597039) =Disease or Syndrome ;
=infection;
CNS DISORDER NOS =Acute Poliomyelitis;
hydrophobia;
infectious encephalitis;
infectious encephalomyelitis;
viral myelinopathy;
infectious meningitis;
latent virus infection;
|
- 20. Nerve palsy, peroneal
- [Paralysis of the nerves located in the legs. ( NCI )] (UMLS (NCI) C0270810) =Disease or Syndrome
| - 45. Nervous System Injury
- [Injury in the central or peripheral nervous system. — 2003 ( NCI )] (UMLS (NCI) C0751792) Neurological Damage;
Trauma, Nervous System =Injury or Poisoning =CNS DISORDER NOS;
trauma =Craniocerebral Trauma;
Injury, spinal cord;
Cerebrovascular Trauma |
- 21. Nerve Paralysis
- (UMLS (NCI) C0262576) =Disease or Syndrome
| - 46. nervous system prosthesis
- [artificial substitute for a missing or non functioning nervous system part or function. ( CSP )] (UMLS (CSP) C0597040) =Medical Device ;
=Prosthesis;
=brain electronic stimulator;
neuromuscular stimulator |
- 22. Nerve Plexus
- [Subdivision of the peripheral nervous system which consists of subdivisions of two or more neural trees, which are interconnected with one another to form a network through which nerve fibers of the constituent nerve trees become regrouped; together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. Examples: cervical plexus, brachial plexus, sacral plexus. ( UWDA )] (UMLS (NCI) C0501403) =Body Part, Organ, or Organ Component
| - 47. nervous system regeneration
- [renewal or physiological repair of damaged tissue in any part of the nervous system. ( CSP )] (UMLS (CSP) C0027756) =Cell Function ;
=Plasticity/Regeneration/Transplantation;
Neural Development =eye regeneration |
- 23. nerve protein
- [ ] (UMLS (CSP) C0027759) =Amino Acid, Peptide, or Protein; Biologically Active Substance =gene product;
=neuropeptide | - 48. nervous system transplantation
- [transferring neural cells, tissues or organs within an individual, between individuals of the same species, or between individuals of different species. ( CSP )] (UMLS (CSP) C0597041) =Therapeutic or Preventive Procedure ;
=transplantation;
Neurological Surgery |
- 24. Nerve Root
- [One of the two bundles of nerve fibers (dorsal and ventral roots) emerging from the spinal cord that join to form each spinal nerve. ( NCI )] (UMLS (NCI) C0228084) =Body Part, Organ, or Organ Component
| - 49. NERVOUSNESS
- (UMLS (ICD9CM) C0027769) =Finding ;
|
- 25. Nerve Sheath Myxoma
- [A benign myxoma of cutaneous nerve sheath origin. Theke is from the Greek theke, sheath. (From Stedman, 25th ed) ( MSH )] (UMLS (NCI) C0206730) =Neoplastic Process =Angiomyxoma;
Neoplasm of Nerve Sheath | |
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