- 1. EGF
- [This gene is involved in the differentiation and proliferation of cells. ( NCI )] (UMLS (NCI) C1367721) EGF Gene;
Epidermal Growth Factor (Beta-Urogastrone) Gene =Gene or Genome | - 5. EGFR Antisense DNA
- [A synthetic sequence of DNA constructed in the antisense orientation to a sequence of DNA in epidermal growth factor receptor (EGFR), a member of the erbB gene family. EGFR antisense DNA suppresses the expression of EGFR by tumor cells, thereby inhibiting tumor cell proliferation and decreasing tumor growth. This agent also appears to reduce the invasiveness of certain breast cancer cells. Members of the erbB gene family are overexpressed in many cancers and play roles in carcinogenesis and the regulation of cell proliferation. (NCI04) ( NCI )] (UMLS (NCI) C0935778) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
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- 2. EGF Repeat Superfamily
- [Many Epidermal Growth Factor Superfamily Proteins are extracellular signaling molecules (ligands) involved in control of target cell proliferation, cell survival, and cell differentiation. The EGF superfamily is characterized by having at least 6 cysteines residues that form disulphide bonds stacked in a ladder-like arrangement, in the order 1-3, 2-4, 5-6, and which are essential for the stability of the EGF fold. Often arranged as tandem repeats in extracellular proteins, the function of the domains remains unclear, but are thought to perform a structural role. ( NCI )] (UMLS (NCI) C1333412) Epidermal Growth Factor Repeat Superfamily;
Epidermal Growth Factor Superfamily Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance ; | - 6. EGFR Antisense DNA/Keyhole Limpet Hemocyanin
- (UMLS (NCI) C1134451) =Therapeutic or Preventive Procedure ;
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- 3. EGFL6
- [This gene plays a role in intercellular communication and may play a role in cell growth. ( NCI )] (UMLS (NCI) C1333331) EGFL6 Gene;
EGF-Like-Domain, Multiple 6 Gene; =Gene or Genome ; | - 7. EGFR Antisense DNA/Sargramostim
- (UMLS (NCI) C1134450) =Therapeutic or Preventive Procedure ;
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- 4. EGFR
- [A secreted form of erbB1 that may have utility as a tumor marker. ( NCI )] (UMLS (NCI) C1368111) sErbB-1;
Soluble ErbB-1; =Amino Acid, Peptide, or Protein; Receptor ◊ [This gene is involved in the epidermal growth factor signal transduction pathway. ( NCI )] (UMLS (NCI) C1414313) EGFR Gene; Epidermal Growth Factor Receptor (Erythroblastic Leukemia Viral (V-ERB-B) Oncogene Homolog, Avian) Gene Gene or Genome | - 8. EGFR Blocker
- [Substances that inhibit Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase, involved with signal transduction pathways, and may be useful in treating tumors that over express EGFR. ( NCI )] (UMLS (NCI) C1443775) EGFR Inhibitor;
EGFR Tyrosine Kinase Inhibitor; EGFR Tyrosine Kinase Inhibitors; EGFR-TK Inhibitor; Epidermal Growth Factor Receptor Inhibitor; Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor; Epidermal Growth-Factor Receptor Tyrosine Kinase Inhibitors =Pharmacologic Substance ; |