[A synthetic radioimmunoconjugate comprised of a humanized anti-interleukin-2 (IL-2) antibody linked to the radioisotope Yttrium 90 with potential antineoplastic activity. Daclizumab binds with high affinity to the Tac (also called CD25) subunit of the IL-2 receptor complex and inhibits the binding of IL-2, thereby blocking the IL-2-mediated activation of lymphocytes. As Yttrium Y 90 daclizumab, daclizumab delivers radiation specifically to lymphocytes that express the IL-2 receptor. (NCI04) ( NCI )]
UMLS (NCI) C0935688Y90 MOAB Anti-Tac
Yttrium Y 90 Daclizumab
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor