- 1. Y 90 Monoclonal Antibody CC49
- [A radioimmunoconjugate of the humanized monoclonal antibody (MoAB) CC49 labeled with Yttrium 90 (Y-90). MoAb CC49 recognizes the pancarcinoma tumor-associated glycoprotein (TAG)-72 with high affinity. Y-90 MoAb CC49 delivers beta particle emitting Y-90 radionuclide directly to tumor cells that express TAG-72, thereby may be used in radioimmunotherapeutic treatment of cancers. ( NCI )] (UMLS (NCI) C0935674) Yttrium Y 90 Monoclonal Antibody CC49;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor | - 4. YM175
- (UMLS (NCI) C0287412) =Organophosphorus Compound; Pharmacologic Substance ;
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- 2. Y90 MOAB Hu3S193
- [A radioimmunotherapeutic agent consisting of a humanized murine monoclonal antibody (hu3S193) directed against the tumor-associated Lewis Y epithelial antigen chelated to the radioisotope yttrium-90. Yttrium Y 90 monoclonal antibody Hu3S193 binds to Lewis Y epithelial antigen-expressing tumor cells, selectively delivering a cytotoxic dose of beta radiation. (NCI04) ( NCI )] (UMLS (NCI) C1328082) Yttrium Y 90 Monoclonal Antibody Hu3S193;
=Pharmacologic Substance; Immunologic Factor | - 5. YM598
- [An orally active synthetic substituted phenylethenesulfonamide. As a selective endothelin A receptor antagonist, YM598 inhibits endothelin-mediated mechanisms involved in tumor cell growth and progression, angiogenesis, and metastasis. (NCI04) ( NCI )] (UMLS (NCI) C1175067) =Organic Chemical ;
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