Dictionaries Armenian-English English-Armenian MeSH Feedback
UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
V V- V0 V1 V2 VA VC VD VE VF VH VI VJ VK VM VN VO VP VQ VR VS VT VU VV VX VY
VIA VIB VIC VID VIE VIG VIL VIM VIN VIO VIP VIR VIS VIT VIV VIZ

Vincristine Sulfate Liposome

[A sphingomyelin/cholesterol liposomal formulation of vincristine sulfate with potential antineoplastic activity. Vincristine, a vinca alkaloid isolated from the plant Vinca rosea, irreversibly binds to and stabilizes tubulin, thereby interrupting microtubule assembly/disassembly dynamics, thereby preventing the formation of the mitotic spindle and leading to cell cycle arrest in metaphase. Liposomal encapsulation prolongs bioavailability of vincristine, increases its delivery to tumor tissues and reduces its toxicity profile. Compared to standard liposomal delivery, sphingosomal drug delivery further increases circulation time of serum drug and enhances drug accumulation at tumor sites, thereby leading to a further increase in efficacy. ( NCI )]
UMLS (NCI) C0935690
 
Organic Chemical
Pharmacologic Substance

Buy website

Medical Clinic. Optician. Pharmacy. Physician. Travel Agency. Hotel reservation. Child Care. Education. Teachers. Lessons. Tests and Exams. Certification. Shopping Center. Store. Real Estate.
Affordable prices from $100.

 home Dictionaries Armenian-English English-Armenian MeSH Feedback  top
© 2008 -2011 Administrator MEDINDEX.AM