[Typically associated with the cell membrane, Protein Hormone Receptors selectively bind with high affinity to genetically-encoded polymerized amino acids in peptide linkage that have regulatory effects on the activity of specific target cells. A ligand-induced conformational and functional change in the receptor alters its interaction with target molecules, leading to changes in cellular physiology through modification of the activity of signal transduction pathways. ( NCI )]
UMLS (NCI) C1335534 - Amino Acid, Peptide, or Protein
- Receptor