P P- P0 P1 P2 P3 P4 P5 P6 P7 P8 P9 PA PB PC PD PE PF PG PH PI PK PL PM PN PO PP PQ PR PS PT PU PV PW PX PY
Prochlorperazine Dimaleate
[The maleate salt form of prochlorperazine, a synthetic, piperazine phenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Prochlorperazine maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension. ( NCI )]
UMLS (NCI) C0033231- Organic Chemical
- Pharmacologic Substance
Relation/PAR: 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine
Relation/CHD: PROCHLORPERAZINE MALEATE 10 MG
PROCHLORPERAZINE MALEATE 25 MG
PROCHLORPERAZINE MALEATE 5 MG
PROCHLORPERAZINE MALEATE 15 MG
PROCHLORPERAZINE MALEATE 30 MG
PROCHLORPERAZINE MALEATE 25 MG
PROCHLORPERAZINE MALEATE 5 MG
PROCHLORPERAZINE MALEATE 15 MG
PROCHLORPERAZINE MALEATE 30 MG
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