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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
P P- P0 P1 P2 P3 P4 P5 P6 P7 P8 P9 PA PB PC PD PE PF PG PH PI PK PL PM PN PO PP PQ PR PS PT PU PV PW PX PY
PO POA POD POI POK POL POM PON POO POP POR POS POT POU POV POW POX

Polyubiquitin B

[Encoded by human UBB Gene, highly conserved 76-aa 8.6-kDa nuclear and cytoplasmic Ubiquitin B is synthesized as a polyubiquitin precursor with head to tail repeats and involved in selective ATP-dependent nonlysosomal degradation of cellular proteins, histone modification, maintenance of chromatin structure, regulation of gene expression, stress response, and ribosome biogenesis. UBB appears to be covalently bound to proteins as a marker for degradation, but also binds to histone H2A in actively transcribed regions and does not cause histone H2A degradation; UBB may be involved in regulation of gene expression. (NCI) ( NCI )]
UMLS (NCI) C1313661
UBB
Ubiquitin B
 
Amino Acid, Peptide, or Protein
Biologically Active Substance


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