P P- P0 P1 P2 P3 P4 P5 P6 P7 P8 P9 PA PB PC PD PE PF PG PH PI PK PL PM PN PO PP PQ PR PS PT PU PV PW PX PY
Patched 2
[Encoded by human PTCH2 Gene (Patched Family), 1203-aa transmembrane protein Patched Homolog 2 is a possible sonic hedgehog receptor, highly similar to PTCH and containing an SSD domain, that may have a role formation of embryonic structures and in epidermal development. The Drosophila patched-hedgehog signaling pathway establishes segment polarity and anterior-posterior orientation. The patched pathway is conserved from fly to vertebrates. With 56% identity to Patched-1, mouse Patched-2 diverges in the hydrophilic region between transmembrane domains 6 and 7 and in a region of the intracellular C terminus. (NCI) ( NCI )]
UMLS (NCI) C1335369Patched Homolog 2
Patched Protein Homolog 2
PTC2
PTCH2
Patched Protein Homolog 2
PTC2
PTCH2
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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