UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
N N- N0 N3 NA NB NC ND NE NF NG NH NI NK NL NM NN NO NP NR NS NT NU NV NX NY NZ
NUA NUB NUC NUD NUL NUM NUN NUR NUT NUV

Nuclear Mitotic Apparatus Protein 1

[Encoded by human NUMA1 Gene, Nuclear Mitotic Apparatus Protein 1 is a structural component of the nucleus containing the largest known protein coiled-coil region, present throughout the interphase nucleus, and localized to the mitotic spindle apparatus. Required for organizing mitotic spindle poles, NUMA1 also appears to have a role in nuclear reassembly in late mitosis. NUMA C-terminal region specifically interacts with nuclear transport factor Importin-beta, which inhibits microtubule aster assembly. Regulating NUMA/Importin-beta interaction, Ran GTPase stimulates assembly of microtubule asters and spindles. (NCI) ( NCI )]
UMLS (NCI) C1335072
NUMA
NUMA1
 
Amino Acid, Peptide, or Protein
Immunologic Factor


 home Dictionaries Armenian-English English-Armenian MeSH Feedback  top
© 2008 -2011 Administrator MEDINDEX.AM