UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
N N- N0 N3 NA NB NC ND NE NF NG NH NI NK NL NM NN NO NP NR NS NT NU NV NX NY NZ
NB1 NBA NBC NBH NBI NBL NBN NBO NBP NBR NBS NBT NBU

N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine Monohydrochloride

[The hydrochloride salt form of tirofiban, a non-peptide tyrosine derivative with anticoagulant property. Tirofiban antagonizes fibrinogen binding to the platelet cell surface receptor, glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. The antagonism prevents adenylyl cyclase activation, which mediated via GP IIb/IIIa receptor complex, and results in decreased levels of cAMP and thereby interferes with platelet membrane function and subsequent platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time. ( NCI )]
UMLS (NCI) C0795668
Tirofiban Hydrochloride
TIROFIBAN HYDROCHLORIDE PREPARATION
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: tirofiban
Relation/CHD: TIROFIBAN HYDROCHLORIDE 250 MCG/ML
TIROFIBAN HYDROCHLORIDE 50 MCG/ML

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