[Encoded by human POU2F2 Gene (POU2 Family), alternative isoforms 1 (478-aa, 51-kD), 2 (466-aa), 3 (462-aa), and 4 (399-aa) of transcription factor OTF-2 contain a DNA binding homeobox domain, bind to octamer motif ATTTGCAT, and regulate Ig gene expression and transcription in several other tissues. OTF-2 also interacts with transcription activators NR3C1, AR, and PGR. Neuronal NOS gene is a target of OTF-2. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C1442823Lymphoid-Specific OTF2
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Octamer Transcription Factor-2
Octamer-Binding Transcription Factor 2
OTF-2
POU Domain, Class 2, Transcription Factor 2
POU Homeodomain Transcription Factor 2
POU2F2
- Amino Acid, Peptide, or Protein
- Biologically Active Substance