LYL1

1. [This gene plays a role in transcriptional regulation and is involved in the pathogenesis of acute lymphoblastic leukemia. ( NCI )]
   UMLS (NCI) C1334354
   
   LYL1 Gene
   Lymphoblastic Leukemia Derived Sequence 1 Gene
    

   Gene or Genome
   

2. [Lymphoblastic Leukemia Derived Sequence 1, encoded by the human LYL1 gene, contains 1 basic helix-loop-helix (bHLH) domain. Efficient DNA binding of this protein requires dimerization with another bHLH protein. This gene is involved in a form of T-cell acute lymphoblastic leukemia (T-ALL) through a chromosomal translocation t(7;9)(q35;p13) which involves LYL1 and T-cell receptor beta chain (TCRB) genes. (from Swiss-Prot) ( NCI )]
   UMLS (NCI) C1334355
   
   Lyl-1 Protein
   Lymphoblastic Leukemia Derived Sequence 1
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance