[A long-acting beta-adrenergic receptor agonist with bronchodilator activity. Formoterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells. ( NCI )]
UMLS (NCI) C0060657 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: [RE102] BRONCHODILATORS, SYMPATHOMIMETIC,INHALATION
Unclassified Ingredients
Relation/CHD: Formamide, N-(2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, rel-,(E)-2-butenedioate(2:1)(salt)