Bamacan
[Chondroitin Sulfate Proteoglycan 6 (CSPG6), encoded by the CSPG6 gene, is an abundant secreted chondroitin sulfate proteoglycan in basement membranes and an intracellular protein. CSPG6 is involved in chromosome cohesion during cell cycle and in DNA repair as a central component of the cohesin complex, which is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis and in chromosome movement. (from LocusLink) ( NCI )]
UMLS (NCI) C0535219- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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