[This protein belongs to the BCL-2 protein family. It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests the roles of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this protein functions as an essential initiator of the apoptosis in thymocyte-negative selection. (from RefSeq Summary) ( NCI )]
UMLS (NCI) C1332396Bcl-2 Interacting Protein Bim
BCL2L11
BCL2-Related Protein 11
BIM
BIMEL
BIML
BimMEL
BOD
- Amino Acid, Peptide, or Protein
- Biologically Active Substance