[Expressed in testis, skeletal muscle, thymus, and spleen by human STK6 Gene (Aurora Ser/Thr Kinase Family), 403-aa 45.8-kDa Serine/Threonine Kinase 6 is a phosphorylated cell cycle-regulated kinase localized on centrosomes in interphase cells and at spindle poles in mitosis. Cell cycle-regulated expression accumulates in G2/M and decrease rapidly thereafter. STK6 appears to be involved in cell cycle-regulated microtubule formation and/or stabilization of the spindle pole region during chromosome segregation in anaphase and telophase. STK6 defects are responsible for centrosome aberrations, including aneuploidy. (NCI) ( NCI )]
UMLS (NCI) C0971285Aurora Kinase A Protein
Aurora/IPL1-Like Kinase
Aurora/IPL1-Related Kinase 1
Aurora-A
Aurora-Related Kinase 1
Breast-Tumor-Amplified Kinase
hARK1
IPL1-Related Kinase
Serine/Threonine Kinase 15
Serine/Threonine Kinase 6
STK15
STK6
- Amino Acid, Peptide, or Protein
- Enzyme