[A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb) 81C6 labeled with an alpha-emitting radionuclide Astatine 211 (At-211), with imaging and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix antigen tenascin (hexabrachion), up-regulated in gliomas and other cancers. Using MoAb 81C6 as a carrier for At-211 results in the targeted imaging and/or destruction of cells expressing tenascin. ( NCI )]
UMLS (NCI) C0796331Astatine At 211 MOAB 81C6
Astatine At 211 Monoclonal Antibody 81C6
Astatine-211 Labelled Anti-Tenascin Monoclonal Antibody 81C6
At 211 Monoclonal Antibody 81C6
- Pharmacologic Substance
- Immunologic Factor