[This protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2, BCLXL, Epstein-Barr virus BHRF1, and adenovirus E1B 19-kD in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. (from RefSeq Summary and OMIM) ( NCI )]
UMLS (NCI) C1332394BCL2-Interacting Killer
BIK
- Amino Acid, Peptide, or Protein
- Biologically Active Substance