[Encoded by human MAPRE1 Gene (MAPRE/RP/EB Family), 268-aa 30-kDa Microtubule-Associated Protein RP/EB Family Member 1 contains a CH domain and a C-terminal domain that binds to APC. In interphase, MAPRE1 localizes to microtubules (growing ends); during mitosis, MAPRE1 is associated with centrosomes and spindle microtubules. MAPRE1 also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. MAPRE1 also interacts with TERF1. MAPRE1 is likely involved in regulation of microtubule structures, microtubule polymerization, spindle function, and chromosome stability. ( NCI )]
UMLS (NCI) C1332099APC-Binding Protein EB1
MAPRE1
Microtubule-Associated Protein, RP/EB Family, Member 1
- Amino Acid, Peptide, or Protein
- Receptor