[A class of antineoplastic oligosaccharide anthracycline antibiotics isolated from various strains of the bacterium Streptomyces galilaeus. These agents display potent antitumor properties due to their ability to intercalate into DNA and inhibit topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04) ( NCI )]
UMLS (NCI) C0919315Aclacinomycins
- Organic Chemical
- Antibiotic