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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AC ACA ACB ACC ACD ACE ACF ACG ACH ACI ACK ACL ACM ACN ACO ACP ACQ ACR ACS ACT ACU ACV ACY

ACK1

[Activated p21cdc42Hs Kinase, encoded by the ACK1 gene, is a non-receptor tyrosine kinase. It binds CDC42 in its GTP-bound activated form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of CDC42. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The encoded protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of CDC42 and which is directly linked to a tyrosine phosphorylation signal transduction pathway. (From LocusLink, OMIM and NCI) ( NCI )]
UMLS (NCI) C1332143
Activated CDC42 kinase 1
Activated p21cdc42Hs Kinase
 
Amino Acid, Peptide, or Protein
Enzyme
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