[A hydrazine derivative of dopa. Carbidopa is a peripheral dopa decarboxylase inhibitor that is used as an adjunct to levodopa administration to prevent peripheral biosynthesis of levodopa to dopamine, thereby reducing peripheral side effects. Carbidopa does not penetrate the blood brain barrier so that levodopa, after it reaches the brain, can be metabolized to dopamine by dopa decarboxylase where it exerts its effect on dopamine receptors. ( NCI )]
UMLS (NCI) C0006982 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: [CN500] ANTIPARKINSON AGENTS
hydrazine
3-Hydroxy-alpha-methyl-L-tyrosine
Relation/CHD: CARBIDOPA 25 MG
CARBIDOPA 50 MG
CARBIDOPA 10 MG
Carbidopa 12.5 MG / entacapone 200 MG / Levodopa 50 MG Oral Tablet
CARBIDOPA 37.5 MG