[Transcription factor SP1 is a DNA-binding protein that interacts with various RNA polymerase II gene promoters containing GC-box elements. It has contiguous zinc finger motifs and requires zinc for sequence-specific binding to DNA. The formation of head segments in Drosophila depends on the homologue of the human transcription factor SP1. (from OMIM 189906 and NCI) ( NCI )] (UMLS (NCI) C0080245) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
[This gene plays a role in transcriptional regulation and is involved in several signal transduction pathways. ( NCI )] (UMLS (NCI) C1335858) SP1 Gene; Sp1 Transcription Factor Gene =Gene or Genome ;