- 1. RNA amplification
- [ ] (UMLS (CSP) C0920648) =Molecular Biology Research Technique ;
| - 15. RNA nucleotidyltransferase
- [Enzymes that catalyze the template-directed incorporation of ribonucleotides into an RNA chain. EC 2.7.7.-. ( MSH )] (UMLS (CSP) C0035673) =Amino Acid, Peptide, or Protein; Enzyme
|
- 2. RNA analysis
- [Molecular biology techniques, including Northern Blot, Differential display, RT-PCR, and RNase protection for qualifying or quantifying RNA. (NCI/OSP) ( NCI )] (UMLS (CSP) C0872262) =Laboratory Procedure; Research Activity
| - 16. RNA Polymerase II Subunit Gene
- [RNA polymerase II subunit genes encode DNA-dependent RNA polymerase II, a complex multisubunit enzyme that is responsible for the transcription of protein-coding genes. Ten to 14 subunits encoded by these genes range in size from 220 to 10 kD. The complex interacts with the promoter regions of genes as well as with a variety of elements and transcription factors to determine essentially all of the parameters that govern transcription, e.g., tissue and development specificity, stress response, etc. A fraction of the large subunit of Pol II (Pol II LS) is ubiquitinated after exposing cells to UV radiation or cisplatin. (NCI) ( NCI )] (UMLS (NCI) C1335628) =Gene or Genome ;
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- 3. RNA Binding
- [RNA Binding is the molecular interaction between an RNA molecule and a macromolecule (usually protein or nucleic acid) for transport, catalysis, localization, or modification of function. ( NCI )] (UMLS (NCI) C1148846) =Genetic Function ;
| - 17. RNA Polymerase II Transcription Factor TAFII140
- [Encoded by human TAF3 Gene, 140-kD nuclear TBP-Associated Factor 140kDa apparently forms complexes with TBP, TAF10, and TAF13, as well as with SAP130 and GCN5. TAF3 contains an N-terminal HFD (interacts with TAF10) and is highly homologous to mouse Tafii140; a PHD finger motif is likely present. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C0968617) TAF140;
TAF3;
TAF3 RNA Polymerase II;
TAFII140;
TATA Box Binding Protein-Associated Factor 140kDa;
TBP-Associated Factor 140kDa =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 4. RNA binding protein
- [mRNA-, viral RNA-, or other RNA-binding proteins specifically designated as such; the polypeptide component of any RIBONUCLEOPROTEIN; may be indexed with or without RIBONUCLEOPROTEIN or its NTs, or RIBOSOMAL PROTEIN. ( CSP )] (UMLS (CSP) C0085177) =Amino Acid, Peptide, or Protein; Biologically Active Substance =ribonucleoprotein;
binding protein | - 18. RNA probe
- [RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes. ( MSH )] (UMLS (CSP) C0035683) =Nucleic Acid, Nucleoside, or Nucleotide; Indicator, Reagent, or Diagnostic Aid
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- 5. RNA biosynthesis
- [synthesis of RNA by living organisms; do not confuse with artificial synthesis, NUCLEIC ACID CHEMICAL SYNTHESIS. ( CSP )] (UMLS (CSP) C1328948) RNA Synthesis =Molecular Function ;
=nucleic acid biosynthesis;
| - 19. RNA purification
- [ ] (UMLS (CSP) C0872264) =Laboratory Procedure ;
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- 6. RNA chemical synthesis
- [The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. [GOC:mah] ( GO )] (UMLS (CSP) C1623415) RNA synthesis =Genetic Function
| - 20. RNA replication
- [ ] (UMLS (CSP) C1328949) =Molecular Function ;
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- 7. RNA Degradation
- [RNA degradation is a regulated cellular biochemical process that involves depolymerization of RNA macromolecules, which affects the RNA content of cells and regulates gene expression. ( NCI )] (UMLS (NCI) C1257756) =Genetic Function ;
| - 21. RNA sequence
- [ ] (UMLS (CSP) C0162327) =Nucleotide Sequence; Nucleic Acid, Nucleoside, or Nucleotide
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- 8. RNA editing
- [A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE). ( MSH )] (UMLS (CSP) C0162782) =Genetic Function ;
| - 22. RNA splicing
- [removal of introns from a primary transcript and the subsequent joining of exons in the production of a mature RNA molecule. ( CSP )] (UMLS (CSP) C0035687) =Genetic Function ;
=posttranscriptional RNA processing;
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- 9. RNA Helicase
- [A family of proteins that promote unwinding of RNA during splicing and translation. EC 2.7.7.-. ( MSH )] (UMLS (NCI) C0084378) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 23. RNA transport
- [RNA transport is the translocation of RNA molecules from one cellular location to another, such as transport from the nucleus to the cytoplasm. ( NCI )] (UMLS (CSP) C0598720) =Cell Function ;
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- 10. RNA library
- [ ] (UMLS (CSP) C0599776) =Gene or Genome ;
| - 24. RNA virus
- [viruses whose genetic material is RNA; can be broken up into several categories, negative sense ssRNA viruses, positive sense ssRNA viruses and naked RNA viruses. ( CSP )] (UMLS (CSP) C0035691) =Virus ;
=virus;
=Arenaviridae;
Astrovirus;
Bunyaviridae;
Coronaviridae;
delta agent;
encephalitis virus;
Influenzavirus;
Picornaviridae;
Reoviridae;
Retroviridae;
satellite virus;
tobacco mosaic virus;
Togaviridae;
hepatitis E virus;
Bromovirus;
Comovirus;
Calicivirus;
Flaviviridae;
Mononegavirales |
- 11. RNA ligase
- [An enzyme that catalyzes the conversion of linear RNA to a circular form by the transfer of the 5'-phosphate to the 3'-hydroxyl terminus. It also catalyzes the covalent joining of two polyribonucleotides in phosphodiester linkage. EC 6.5.1.3. ( MSH )] (UMLS (CSP) C0032589) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 25. RNA, Ribosomal 1 Gene
- [This gene is involved in transcription of ribosomal RNA which plays a role in protein synthesis. ( NCI )] (UMLS (NCI) C1335630) RNR1;
RNR1 Gene =Gene or Genome ;
|
- 12. RNA marker
- [ ] (UMLS (CSP) C0872263) =Laboratory or Test Result; Sign or Symptom
| - 26. RNase III Family Protein
- [Eukaryotic RNase-III Family Proteins are a group of related protein orthologs of bacterial dsRNA-specific RNase III. The basic functions of Yeast RNase III in maturation of snRNAs, snoRNAs, and rRNA appear to be widely conserved. Ubiquitous human nuclear Ribonuclease III is involved in pre-rRNA processing and endonucleolytically cleaves double-strand RNA to 5'-phosphomonoester. ( NCI )] (UMLS (NCI) C1335791) =Amino Acid, Peptide, or Protein; Enzyme
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- 13. RNA Metabolism: Processing and Transport
- [Modifications of primary RNA transcripts including: splicing, cleavage, base modification, capping and the addition of poly A (mRNA) or CCA (tRNA) tails. The primary transcript is the RNA molecule containing the exact sequence of bases (with U substituting for T in DNA) found in the nontemplate strand of transcribed DNA. ( NCI )] (UMLS (NCI) C1158728) RNA Processing;
=Genetic Function | - 27. RNase protection assay
- [antisense RNA corresponding to known genes is hybridized to unknown samples, then the sample is digested with a single-strand-specific RNase; any surviving RNA must have been complementary to the antisense, and therefore transcribed from the gene of interest. ( CSP )] (UMLS (CSP) C0597416) =Molecular Biology Research Technique =chromosome mapping;
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- 14. RNA methylation
- [addition of methyl groups to RNA. ( CSP )] (UMLS (CSP) C0597415) =Genetic Function ;
=nucleic acid methylation;
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