- 1. rib
- [any of the paired elastic arches of bone that extend from the thoracic vertebrae toward the median line on the ventral aspect of the trunk, forming the major part of the thoracic skeleton; collectively called costae. ( CSP )] (UMLS (CSP) C0035561) =Body Part, Organ, or Organ Component ;
=Body Part;
bone | - 24. ribose phosphate
- [ ] (UMLS (CSP) C0597412) =Carbohydrate ;
=pentose phosphate;
|
- 2. Rib Head
- (UMLS (NCI) C0222806) =Body Part, Organ, or Organ Component
| - 25. ribose phosphate pyrophosphokinase
- [An enzyme that catalyzes the formation of phosphoribosyl pyrophosphate from ATP and ribose-5-phosphate. EC 2.7.6.1. ( MSH )] (UMLS (CSP) C0035551) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 3. Rib Shaft
- (UMLS (NCI) C0448161) =Body Part, Organ, or Organ Component
| - 26. riboside
- [any glycoside containing ribose as the sugar component. ( CSP )] (UMLS (CSP) C0597413) =Carbohydrate ;
=Glycoside;
|
- 4. Rib Tubercle
- (UMLS (NCI) C0222809) =Body Location or Region
| - 27. Ribosomal
- [class of multicomponent structures found in all cells, in mitochondria, and chloroplasts with roles both in the genetic translation of transcripts and in the manufacture and secretion of the proteins. ( CSP )] (UMLS (NCI) C0035553) =Cell Component =cell component;
=polyribosome;
|
- 5. RIB/STERNUM/CLAVIC X-RAY
- [ ] (UMLS (ICD9CM) C0202819) =Diagnostic Procedure
| - 28. ribosomal protein
- [diverse family of proteins found in ribosomes. ( CSP )] (UMLS (CSP) C0035552) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=nucleoprotein;
|
- 6. Riboazauracil
- (UMLS (NCI) C0878257) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 29. Ribosomal Protein L10 Gene
- [This gene plays a role in protein biosynthesis. It is also involved in signal transduction. ( NCI )] (UMLS (NCI) C1335635) RPL10;
RPL10 Gene =Gene or Genome ;
|
- 7. Riboflavin Metabolism
- [The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). [GOC:jl, http://www.indstate.edu/thcme/mw…g/vitamins.html] ( GO )] (UMLS (NCI) C1159440) Riboflavin Metabolism Pathway =Molecular Function
| - 30. Ribosomal Protein L13 Gene
- [This gene plays a role in transcription of ribosomal RNA which plays a role in protein synthesis. ( NCI )] (UMLS (NCI) C1335636) RPL13;
RPL13 Gene =Gene or Genome ;
|
- 8. Ribonuclease
- [Enzymes that catalyze the hydrolysis of RNA ( NCI )] (UMLS (NCI) C0035542) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 31. Ribosomal Protein L19 Gene
- [This gene plays a role in RNA binding and protein translation. ( NCI )] (UMLS (NCI) C1335637) RPL19;
RPL19 Gene =Gene or Genome ;
|
- 9. Ribonuclease Gene
- [Ribonuclease Genes encode (Ribo)nucleases that specifically catalyze the cleavage of phosphate ester linkages in ribonucleic acids; endoribonucleases cleave internal bonds and exoribonucleases cleave bonds at termini. (NCI) ( NCI )] (UMLS (NCI) C1335782) =Gene or Genome ;
| - 32. Ribosomal Protein L29 Gene
- [This gene is involved in RNA binding and protein synthesis. ( NCI )] (UMLS (NCI) C1335638) RPL29;
RPL29 Gene =Gene or Genome ;
|
- 10. ribonuclease H
- [specifically cleaves the RNA moiety of RNA:DNA hybrids. ( CSP )] (UMLS (CSP) C0085431) =Amino Acid, Peptide, or Protein; Enzyme =Endoribonuclease;
| - 33. Ribosomal Protein L7A Gene
- [This gene plays a role in protein biosynthesis. It is also involved in the inhibition of transactivation of transcription by nuclear hormone receptors. ( NCI )] (UMLS (NCI) C1335639) RPL7A;
RPL7A Gene =Gene or Genome ;
|
- 11. ribonuclease P
- [an RNA containing enzyme, essential for tRNA processing generates 5' terminal of mature tRNA molecule. ( CSP )] (UMLS (CSP) C0073243) =Amino Acid, Peptide, or Protein; Enzyme ;
=Endoribonuclease;
| - 34. Ribosomal Protein L8 Gene
- [This gene is involved in RNA binding and protein translation. ( NCI )] (UMLS (NCI) C1335640) RPL8;
RPL8 Gene =Gene or Genome ;
|
- 12. Ribonucleic acid
- [ribonucleic acid; polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached; RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. ( CSP )] (UMLS (NCI) C0035668) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance =Nucleic Acid;
=bacterial RNA;
double stranded RNA;
heterogeneous nuclear RNA;
Messenger RNA;
ribosomal RNA;
small nuclear RNA;
transfer RNA;
virus RNA;
complementary RNA;
catalytic RNA;
siRNA;
MicroRNA;
Post-Transcriptional Gene Silencing | - 35. Ribosomal Protein S19 Gene
- [This gene plays a role in erythropoiesis and embryogenesis. ( NCI )] (UMLS (NCI) C1335641) RPS19;
RPS19 Gene =Gene or Genome ;
|
- 13. ribonucleoprotein
- [substance composed of both protein and ribonucleic acid. ( CSP )] (UMLS (CSP) C0035544) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=nucleoprotein;
=calreticulin;
RNA binding protein;
heterogeneous nuclear ribonucleoprotein;
| - 36. Ribosomal Protein S27 (Metallopanstimulin 1) Gene
- [This gene is involved in DNA binding, RNA binding and protein synthesis. It also plays a role in regulation of cell proliferation. ( NCI )] (UMLS (NCI) C1335642) RPS27;
RPS27 Gene =Gene or Genome ;
|
- 14. ribonucleoside
- [nucleoside in which the purine or pyrimidine base is combined with ribose. ( CSP )] (UMLS (CSP) C0035546) =Nucleic Acid, Nucleoside, or Nucleotide =nucleoside;
=adenosine;
cytidine;
guanosine;
inosine;
1-.beta.-D-Ribofuranosyl-1H-1,2, 4-triazole-3-carboxamide;
4-Amino-7.beta.-D-ribofuranosyl-7H-pyrrolo(2, 3-d)pyrimidine;
tunicamycin;
UR;
adenosine;
cytidine;
formycin;
inosine;
1-.beta.-D-Ribofuranosyl-1H-1,2, 4-triazole-3-carboxamide;
UR | - 37. Ribosomal Protein S3 Gene
- [This gene plays a role in DNA repair and positive regulation of apoptosis. ( NCI )] (UMLS (NCI) C1335643) RPS3;
RPS3 Gene =Gene or Genome ;
|
- 15. Ribonucleoside-Diphosphate Reductase M1 Chain
- [Encoded by human RRM1 Gene, Ribonucleoside-Diphosphate Reductase M1 Chain is 1 of 2 ribonucleoside-diphosphate reductase subunits, a heterodimeric cytoplasmic enzyme essential in dividing cells that reduces ribonucleotides to deoxyribonucleotide precursors for DNA synthesis in S phase. Complex allosteric control, mediated by deoxynucleoside triphosphates, and by ATP bound to the M1 subunit prevents DNA replication and cell proliferation. A substrate specificity site and a catalytic activity site regulate enzyme activity. A substrate-binding catalytic site on M1 is only formed in the presence of M2. Enzyme activity closely correlates with the cellular rate of growth and appears to vary with the cell cycle. RRM1 functions as a metastasis suppressor gene through induction of PTEN expression and PTEN-regulated pathways. (from Swiss-Prot, OMIM, LocusLink and NCI) ( NCI )] (UMLS (NCI) C1259395) Ribonucleotide Reductase Large Chain;
Ribonucleotide Reductase M1 Polypeptide;
Ribonucleotide Reductase R1 Subunit;
RRM1;
RRM1 Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 38. Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 Gene
- [This gene is involved in the regulation of cell growth and proliferation. ( NCI )] (UMLS (NCI) C1335645) RPS6KB2;
RPS6KB2 Gene =Gene or Genome ;
|
- 16. ribonucleotide
- [nucleotide in which the purine or pyrimidine base is combined with ribose. ( CSP )] (UMLS (CSP) C0035548) =Nucleic Acid, Nucleoside, or Nucleotide =nucleotide;
=FAD;
flavin mononucleotide;
adenine nucleotide;
| - 39. Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 Gene
- [This gene plays a role in the cellular signaling that occurs in response to mitogenic or stress stimuli. ( NCI )] (UMLS (NCI) C1419746) RPS6KA5;
RPS6KA5 Gene =Gene or Genome |
- 17. Ribonucleotide Reductase Inhibitor
- [Substances that inhibit Ribonucleotide Reductase, an enzyme converting ribonucleoside diphosphates to deoxyribonucleotide diphosphate precursors for de novo DNA synthesis, causing inhibition of DNA synthesis and cell growth. ( NCI )] (UMLS (NCI) C1373035) Ribonucleotide Reductase Inhibitors;
=Pharmacologic Substance; Biologically Active Substance =Inhibitors, Nucleic Acid Synthesis;
| - 40. Ribosomal Protein SA Gene
- [This gene plays a role in several cellular processes including movement, signaling, and differentiation. ( NCI )] (UMLS (NCI) C1334330) RPSA;
RPSA Gene;
=Gene or Genome ;
|
- 18. Ribonucleotide Reductase M1 Polypeptide Gene
- [This gene plays a role in the inhibition of cell migration, invasion, and metastasis. ( NCI )] (UMLS (NCI) C1335648) RRM1;
RRM1 Gene =Gene or Genome ;
| - 41. ribosomal RNA
- [most abundant form of RNA; together with proteins, it forms the ribosomes, playing a structural role and also a role in ribosomal binding of mRNA and tRNAs; individual chains are conventionally designated by their sedimentation coefficients; in eukaryotes, four large chains exist, synthesized in the nucleolus and constituting about 50 percent of the ribosome. ( CSP )] (UMLS (CSP) C0035701) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance =Ribonucleic acid;
|
- 19. Ribonucleotide Reductase M2 Polypeptide Gene
- [This gene is involved in the promotion of cell cycle-specific gene expression. ( NCI )] (UMLS (NCI) C1335649) RRM2;
RRM2 Gene =Gene or Genome ;
| - 42. Ribosomal RNA-1
- [Encoded by human RNR1 Gene, RNA Ribosomal 1 is a ribosomal RNA associated with proteins as structural components of a ribosome where polypeptides are produced by interacting with tRNA and mRNA. (From NCI) ( NCI )] (UMLS (NCI) C1335785) RNA, Ribosomal 1;
RNR1;
=Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance |
- 20. Ribonucleotide Reductase Subunit
- [Encoded by Ribonucleotide Reductase Subunit Genes (RRM1 and RRM2), the M1 Chain and M2 Chain subunits compose Ribonucleoside-Diphosphate Reductase, a heterodimeric cytoplasmic enzyme essential in dividing cells that reduces ribonucleotides to deoxyribonucleotide precursors for DNA synthesis in S phase. Enzyme activity closely correlates with the cellular rate of growth and appears to vary with the cell cycle. A substrate site and catalytic site regulate enzyme activity. Allosteric control by deoxynucleoside triphosphates and by ATP bound to M1 prevents DNA replication and cell proliferation. An M1 catalytic site only forms in the presence of M2. M2 synthesis is cell-cycle dependent. p53 regulates ribonucleotide reductase by interaction with p53R2 as well as the M2 subunit. (NCI) ( NCI )] (UMLS (NCI) C1335783) =Amino Acid, Peptide, or Protein; Enzyme
| - 43. Ribosome Subunit Gene
- [Ribosome Subunit Genes encode Ribosomal Proteins, present in either the small or the large ribosomal subunit and involved in protein synthesis. In eukaryotes there are 50 proteins in the large subunit and 33 in the small subunit. (NCI) ( NCI )] (UMLS (NCI) C1335786) =Gene or Genome ;
|
- 21. Ribonucleotide Reductase Subunit Gene
- [Ribonucleotide Reductase Subunit Genes (RRM1 and RRM2) encode the M1 Chain and M2 Chain subunits of Ribonucleoside-Diphosphate Reductase, a heterodimeric cytoplasmic enzyme essential in dividing cells that reduces ribonucleotides to deoxyribonucleotide precursors for DNA synthesis in S phase. Enzyme activity closely correlates with the cellular rate of growth and appears to vary with the cell cycle. A substrate site and catalytic site regulate enzyme activity. Allosteric control by deoxynucleoside triphosphates and by ATP bound to M1 prevents DNA replication and cell proliferation. An M1 catalytic site only forms in the presence of M2. M2 synthesis is cell-cycle dependent. p53 regulates ribonucleotide reductase by interaction with p53R2 as well as the M2 subunit. (NCI) ( NCI )] (UMLS (NCI) C1335784) =Gene or Genome ;
| - 44. ribosyltransferase
- [ ] (UMLS (CSP) C0599091) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 22. ribopolynucleotide
- [ ] (UMLS (CSP) C0599163) =Nucleic Acid, Nucleoside, or Nucleotide ;
| - 45. Riboxamide
- [An anticancer drug being studied to stop cell growth. ( NCI )] (UMLS (NCI) C0076656) =Organic Chemical; Pharmacologic Substance
|
- 23. ribose
- [aldopentose found in riboflavin and ribonucleic acid (RNA) as well as in free ribonucleosides and ribonucleotides. ( CSP )] (UMLS (CSP) C0035549) =Carbohydrate; Biologically Active Substance ;
=pentose;
=deoxyribose;
| |
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