- 1. MLN2704
- [An immunoconjugate that consists of a humanized monoclonal antibody (MLN591), directed against prostate-specific membrane antigen linked to a maytansinoid (DM1). The monoclonal antibody moiety of MLN2704 binds to tumor cells expressing prostate-specific membrane antigen; MLN274 is then internalized into the tumor cell where the DM1 maytansinoid moiety binds to tubulin and inhibits tubulin polymerization and microtubule assembly, resulting in a disruption of microtubule activity and cell division, and cell death. (NCI04) ( NCI )] (UMLS (NCI) C1327945) MLN591DM1 =Organic Chemical; Pharmacologic Substance; Immunologic Factor
| - 2. MLN341
- (UMLS (NCI) C1328654) =Organic Chemical; Pharmacologic Substance
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