UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM - Terms starting with ‘E’

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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM

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1. IMEXON: [A 2-cyanoaziridine derivative with antitumor activity in multiple myeloma. Although its mechanism of action is not clearly known, imexon may induce apoptosis via a pathway involving cleaved caspase-3, caspase-9, and/or caspase-8. Other cytotoxic mechanisms of action of this agent may involve thiol depletion, generation of reactive oxygen species (ROS), and decreases in the mitochondrial membrane potential. (NCI04) ( NCI )] (UMLS (NCI) C0123374) =Organic Chemical; Pharmacologic Substance ;

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