- 1. GRB10
- [Grb10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. It interacts with IGF1R, PDGFRB, and EGFR and binds to the Raf-1 and MEK1 kinases. Its cellular role is still unclear and a positive as well as an inhibitory role in mitogenesis depending on the cell context has been implicated. Grb10 may regulate signaling between plasma membrane receptors and the apoptosis-inducing machinery on the mitochondrial outer membrane. (from LocusLink, J Biol Chem 1999;274:35719-24, and Mol Cell Biol 1999;19:6217-28) ( NCI )] (UMLS (NCI) C0296936) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 4. GRB14
- [This gene is involved in signal transduction and mediation of the cellular response to insulin. ( NCI )] (UMLS (NCI) C1333706) GRB14 Gene;
Growth Factor Receptor-Bound Protein 14 Gene =Gene or Genome |
- 2. GRB10
- [This gene is involved in signal transduction. It plays a role in the regulation of both apoptosis and cell proliferation. ( NCI )] (UMLS (NCI) C1366512) GRB10 Gene;
Growth Factor Receptor-Bound Protein 10 Gene =Gene or Genome | - 5. GRB2
- [This gene plays a role in signal transduction and intercellular signaling. ( NCI )] (UMLS (NCI) C1333707) GRB2 Gene;
Growth Factor Receptor-Bound Protein 2 Gene =Gene or Genome |
- 3. GRB14
- [Member of the GRB7 family of adapter proteins; identified as a partner of the insulin receptor where it acts as a modulator of insulin signaling. (from J Biol Chem 2002;277:4845-52) ( NCI )] (UMLS (NCI) C0390030) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 6. GRB7
- [This gene is involved in signal transduction and protein binding. ( NCI )] (UMLS (NCI) C1333708) GRB7 Gene;
Growth Factor Receptor-Bound Protein 7 Gene =Gene or Genome |
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