- 1. G Protein Gene
- [Classification. Proto-oncogenes that code for G proteins. ( NCI )] (UMLS (NCI) C0812324) Proto-Oncogene, G-Protein;
=Gene or Genome ;
| - 18. G Protein-Coupled Receptor Gene
- [These genes encodes G protein-coupled receptors (GPRs or GPCRs). GPRs contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. (from OMIM 604161) ( NCI )] (UMLS (NCI) C1367690) GPCR;
GPR =Gene or Genome |
- 2. G Protein Pathway Suppressor 1 Gene
- [This gene is involved in suppression of signal transduction. ( NCI )] (UMLS (NCI) C1333702) GPS1;
GPS1 Gene =Gene or Genome | - 19. G Protein-Coupled Receptor Kinase 1 Gene
- [This gene is involved in sensory transduction necessary for vision. ( NCI )] (UMLS (NCI) C1335620) GRK1;
GRK1 Gene =Gene or Genome ;
|
- 3. G Protein Pathway Suppressor 2
- [G Protein Pathway Suppressor 2 Protein (GPS2), encoded by the GPS2 gene, are two distinct protein isoforms from specified transcript variants. In budding yeast, GPS is a suppressor of lethal G-protein subunit-activating mutations in the pheromone response pathway. In mammalian cells, GPS2 has been shown to suppress RAS- and mitogen-activated protein kinase-mediated signaling and interfere c-Jun N-terminal Kinase activation. GPS2 is also involved in transcriptional activation of papillomavirus genes through its interaction with virus E2 and E6 proteins. (from LocusLink) ( NCI )] (UMLS (NCI) C0533630) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 20. G Protein-Coupled Receptor Kinase 1B
- [Encoded by human RHOK Gene (GPRK Family), 563-aa 64-kDa membrane-bound Rhodopsin Kinase, containing 1 RGS domain, regulates GPCR rhodopsin desensitization and initiates rhodopsin deactivation by phosphorylation following light stimulation. (NCI) ( NCI )] (UMLS (NCI) C1384522) GRK1;
Rhodopsin Kinase;
RHOK;
RK;
=Amino Acid, Peptide, or Protein; Enzyme |
- 4. G Protein Pathway Suppressor 2 Gene
- [This gene plays a role in suppression of signal transduction. ( NCI )] (UMLS (NCI) C1333703) GPS2;
GPS2 Gene =Gene or Genome | - 21. G Protein-Coupled Receptor Kinase 4 Gene
- [This gene is involved in signal transduction. ( NCI )] (UMLS (NCI) C1333698) GRK4;
GRK4 Gene =Gene or Genome |
- 5. G Protein, Beta-2 Subunit
- [Expressed in oocytes and blastocysts by human GNB2 Gene, 340-aa 37-kDa Guanine Nucleotide Binding Protein Beta 2 is a heterotrimeric G protein beta subunit with 7 WD repeats and involved in transmembrane signaling as a transducer that regulates G protein alpha subunits and integrates signals between receptors and effector proteins. The G protein beta and gamma subunits are required for GTPase activity, for GTP replacement of GDP, and for G protein/effector interaction. (NCI) ( NCI )] (UMLS (NCI) C1333885) GNB2;
Guanine Nucleotide Binding Protein Beta 2;
Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 2;
Signal-Transducing Guanine Nucleotide-Binding Regulatory Protein Beta Subunit;
Transducin Beta Chain 2;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 22. G Protein-Coupled Receptor Kinase 5 Gene
- [This gene plays a role in signal transduction and the regulation of polymorphonuclear leukocyte motility. ( NCI )] (UMLS (NCI) C1333699) GRK5;
GRK5 Gene =Gene or Genome |
- 6. G Protein, Beta-3 Subunit
- [Encoded by human GNB3 Gene, 340-aa 37-kDa Guanine Nucleotide Binding Protein Beta 3 is a heterotrimeric G protein beta subunit with 7 WD repeats and involved in transmembrane signaling as a transducer that regulates G protein alpha subunits and integrates signals between receptors and effector proteins. The G protein beta and gamma subunits are required for GTPase activity, for GTP replacement of GDP, and for G protein/effector interaction. A splicing polymorphism is associated with essential hypertension and obesity. ( NCI )] (UMLS (NCI) C1122941) GNB3;
GTP-Binding Regulatory Protein Beta-3 Chain;
Guanine Nucleotide Binding Protein Beta 3;
Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3;
Transducin Beta Chain 3 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 23. G Protein-Coupled Receptor Kinase 6 Gene
- [This gene is involved in signal transduction. ( NCI )] (UMLS (NCI) C1333700) GRK6;
GRK6 Gene =Gene or Genome |
- 7. G Protein-Coupled Receptor 109B Gene
- [This gene is involved in G protein-coupled receptor signal transduction and nicotinic acid receptor activity. ( NCI )] (UMLS (NCI) C1333902) GPR109B;
GPR109B Gene =Gene or Genome ;
| - 24. G Protein-Coupled Receptor Kinase 7 Gene
- [This gene plays a role in signal transduction within the retina. ( NCI )] (UMLS (NCI) C1333701) GRK7;
GRK7 Gene =Gene or Genome |
- 8. G Protein-Coupled Receptor 17
- [G Protein-Coupled Receptor 17, encoded by the GPR17 gene, is a putative receptor for purines coupled to G-proteins. Two alternative products are primarily expressed in brain. This Integral membrane protein belongs to family 1 of G-protein coupled receptors. (from Swiss-Prot and OMIM) ( NCI )] (UMLS (NCI) C1333731) GPR17;
P2Y-Like Receptor;
Probable P2Y Purinoceptor GPR17;
R12 =Amino Acid, Peptide, or Protein; Receptor | - 25. G Protein-Coupled Receptor Kinase Gene
- [G Protein-Coupled Receptor Kinase Genes encode G Protein-Coupled Receptor Kinases, which regulate through phosphorylation the signaling function of G protein-coupled receptors and signal transduction. (NCI) ( NCI )] (UMLS (NCI) C1333739) =Gene or Genome ;
|
- 9. G Protein-Coupled Receptor 17 Gene
- [This gene is involved in G protein-coupled receptor signal transduction but an exact function is not known. ( NCI )] (UMLS (NCI) C1333691) GPR17;
GPR17 Gene;
=Gene or Genome | - 26. G Protein-Coupled Receptor Kinase Interactor 1 Gene
- [This gene plays a role in signal transduction and cytoskeletal remodeling. ( NCI )] (UMLS (NCI) C1333676) GIT1;
GIT1 Gene =Gene or Genome ;
|
- 10. G Protein-Coupled Receptor 32
- [Encoded by human GPR32 Gene (GPCR1 Family), 356-aa 40-kDa integral membrane protein G Protein-Coupled Receptor 32 is an orphan receptor with greatest similarity to chemoattractant receptors, particularly the formylpeptide receptor (FPR1). (NCI) ( NCI )] (UMLS (NCI) C0757496) GPR32;
Probable G Protein-Coupled Receptor GPR32;
=Amino Acid, Peptide, or Protein; Receptor ;
| - 27. G Protein-Coupled Receptor Kinase Interactor 2 Gene
- [This gene is involved in signal transduction and regulation of receptor signaling. ( NCI )] (UMLS (NCI) C1333677) GIT2;
GIT2 Gene;
=Gene or Genome ;
|
- 11. G Protein-Coupled Receptor 32 Gene
- [This gene is involved in G protein-coupled receptor signal transduction. ( NCI )] (UMLS (NCI) C1333693) GPR32;
GPR32 Gene =Gene or Genome | - 28. G Protein-Coupled Receptor Kinase-Interactor 1
- [G Protein-Coupled Receptor Kinase-Interactor 1: GIT1 is a multidomain protein that is thought to function as an integrator of signaling pathways controlling vesicle trafficking, adhesion and cytoskeletal organization. (from J Cell Sci 2002 Apr 1;115(Pt 7):1497-510) ( NCI )] (UMLS (NCI) C1333736) GIT1;
=Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 12. G Protein-Coupled Receptor 39
- [Widely expressed by human GPR39 Gene (GPCR1 Family), 453-aa 51-kDa 7-transmembrane orphan G Protein-Coupled Receptor 39 exhibits high homology to the growth hormone secretagogue receptor (GHSR). (NCI) ( NCI )] (UMLS (NCI) C1333733) GPR39;
Putative G Protein-Coupled Receptor GPR39 =Amino Acid, Peptide, or Protein; Receptor | - 29. G Protein-Coupled Receptor, Family C, Group 5, Member C
- [Expressed in stomach, kidney, liver, lung, pancreas, central nervous system, and prostate by human GPRC5C Gene (GPCRc Family), 441-aa 48-kDa 7-transmembrane G Protein-Coupled Receptor Family C Group 5 Member C has an extracellular N-terminal domain, an intracellular C-terminal domain, and conserved cysteines residues. The specific protein function is unknown; it may mediate retinoic acid effects on G protein signal transduction. (NCI) ( NCI )] (UMLS (NCI) C0963060) GPRC5C;
Orphan G-Protein Coupled Receptor;
Retinoic Acid Responsive Gene Protein;
=Amino Acid, Peptide, or Protein; Receptor ;
|
- 13. G Protein-Coupled Receptor 39 Gene
- [This gene is involved in G protein-coupled receptor signal transduction and the regulation of growth factor release. ( NCI )] (UMLS (NCI) C1333694) GPR39;
GPR39 Gene =Gene or Genome | - 30. G Protein-Coupled Receptor, Family C, Group 5, Member C Gene
- [This gene plays a role in G protein-coupled receptor signal transduction but the specific function of this protein is unknown. ( NCI )] (UMLS (NCI) C1333697) GPRC5C;
GPRC5C Gene =Gene or Genome |
- 14. G Protein-Coupled Receptor 54
- [Encoded by human GPR54 Gene, 395-aa 43-kDa G Protein-Coupled Receptor 54 is a Gq/11-coupled receptor for endogenous KISS1 (Metastin), which appears to inhibit chemotaxis. (NCI) ( NCI )] (UMLS (NCI) C1097812) G Protein-Coupled Receptor AXOR12;
GPR54;
G-Protein-Coupled Receptor GPR54;
Metastin Receptor;
=Amino Acid, Peptide, or Protein; Receptor ;
| - 31. G15 Protein
- [Widely expressed by human RBM5 Gene, 815-aa 92-kDa RNA Binding Motif Protein 5 contains 2 RRM domains, a G-patch domain, and a RANBP2-type zinc finger and specifically binds to RNA. (NCI) ( NCI )] (UMLS (NCI) C0907884) Putative Tumor Suppressor LUCA15;
RNA Binding Motif Protein 5;
RNA-Binding Protein 5 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 15. G Protein-Coupled Receptor 54 Gene
- [This gene plays a role in G protein-coupled receptor signal transduction and is associated with thyroid carcinoma. ( NCI )] (UMLS (NCI) C1333695) GPR54;
GPR54 Gene =Gene or Genome | - 32. GPR
- [Rod-shaped bacteria that retain the crystal violet stain when treated by Gram's method. ( NCI )] (UMLS (NCI) C0085498) =Bacterium
|
- 16. G Protein-Coupled Receptor 68
- [G Protein-Coupled Receptor 68, encoded by the GPR68 gene, belongs to family 1 of G-protein coupled receptors. This integral membrane protein is a receptor for sphingosylphosphorylcholine and couples to G proteins that stimulate phosphoinositide hydrolysis. It acts as a proton-sensing receptor stimulating inositol phosphate formation and is involved in pH homeostasis. The skeleton participates in pH homeostasis as a buffering organ and osteoblasts respond to pH changes in the physiologic range. This receptor represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. (from Swiss-Prot and OMIM) ( NCI )] (UMLS (NCI) C1259265) GPR68;
OGR-1;
Ovarian Cancer G Protein-Coupled Receptor 1;
Sphingosylphosphorylcholine Receptor;
=Amino Acid, Peptide, or Protein; Receptor ;
| - 33. GPRC5A
- [Encoded by human RAI3 Gene (GPCR3 Family), 357-aa 40-kDa Retinoic Acid Induced 3 protein contains 7 predicted GPCR-signature transmembrane domains and a potential N-linked glycosylation site. Likely involved in the interaction between retinoid acid and G protein signaling pathways, RAI3 may play a role in embryonic development and epithelial cell differentiation. (NCI) ( NCI )] (UMLS (NCI) C0762318) RAI3;
RAIG1;
Retinoic Acid Induced 3 =Amino Acid, Peptide, or Protein; Receptor |
- 17. G Protein-Coupled Receptor 68 Gene
- [This gene is involved in G protein-coupled receptor signal transduction and pH homeostasis. ( NCI )] (UMLS (NCI) C1333696) GPR68;
GPR68 Gene =Gene or Genome | |
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