- 1. GL331
- [An epipodophyllotoxin analogue possessing antineoplastic properties. GL331 binds to and inhibits topoisomerase II, resulting in the accumulation of single- or double-strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death. (NCI) ( NCI )] (UMLS (NCI) C0908996) =Organic Chemical; Pharmacologic Substance ;
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