UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM - Terms starting with ‘K’

selected terms: 3

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1. ERK: [MAP kinase gene products act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. (LocusLink) ( NCI )] (UMLS (NCI) C1370600) Extracellular Signal-Regulated Kinase Gene;
MAP Kinase Gene;
MAPK;
Mitogen-Activated Protein Kinase Gene =Gene or Genome

3. ERK 2: [Encoded by Human MAPK1 Gene (MAPK Family) as alternative p40 and p41 isoforms, Mitogen-Activated Protein Kinase 1 is a proline-directed Ser/Thr kinase activated in response to extracellular stimuli and widely involved in signal transduction as an integration point for multiple biochemical signals and as part of complex protein kinase cascades involved in a cell proliferation, differentiation, transcription regulation, and development. Autophosphorylated and phosphorylated/activated by upstream kinases on threonine and tyrosine residues, MAPK1 forms dimers with phosphorylated and unphosphorylated ERK partners, translocates to the nucleus and phosphorylates target transcription factors. MAPK1 phosphorylates MAP2, MBP, and ELK-1. (NCI) ( NCI )] (UMLS (CSP) C0170168) =Amino Acid, Peptide, or Protein; Enzyme ;

2. ERK 1: [A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS. ( MSH )] (UMLS (CSP) C0082529) =Amino Acid, Peptide, or Protein; Enzyme ;

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