[strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups; although structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA; they are generally highly toxic but include among their number many widely used and effective antineoplastic agents; use this term to cover the chemical warfare agent mustard gas. ( CSP )]
UMLS (CSP) C0026873 - Organic Chemical
- Pharmacologic Substance
- Hazardous or Poisonous Substance
Relation/PAR: Halogenated Hydrocarbon
Relation/CHD: Bis(2-chloroethyl)methylamine
Nitrogen Mustard Compound