[The human thyroid hormone receptor-associated protein (TRAP)-Mediator complex was originally identified as a large multimeric complex that copurifies with the thyroid hormone receptor (TR) from HeLa cells and markedly enhances TR-mediated transcription in vitro. More recent studies have implicated TRAP-Mediator as a coactivator for a broad range of nuclear hormone receptors as well as other classes of transcriptional activators. TRAP-Mediator may play an important coregulatory role in androgen receptor-mediated gene expression. (from J Biol Chem. 2002;277:42852-8) ( NCI )]
UMLS (NCI) C1336668TRAP Complex
TRAP Mediator
TRAP Mediator Complex
TRAP/Mediator Complex
- Amino Acid, Peptide, or Protein
- Biologically Active Substance