Dictionaries Armenian-English English-Armenian MeSH Feedback
UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
R R R- R0 R1 R2 R3 R4 RA RB RC RD RE RF RG RH RI RK RM RN RO RP RQ RR RS RT RU RV RW RX RY
RE RE- REA REB REC RED REE REF REG REH REI REJ REL REM REN REO REP REQ RER RES RET REU REV REW REX

Retinoic Acid Receptor RXR-Alpha

[Expressed in liver, lung, kidney, and heart by human RXRA Gene (NR2/RXR Family), 462-aa 51-kDa nuclear Retinoid X Receptor Alpha is a transcriptional regulator composed of N-terminal modulating domain, DNA-binding domain, and C-terminal 9-cis RA-binding domain. Involved in the retinoic acid response pathway, RXRA interacts with NCOA3 and NCOA6 coactivators and mediates RA biological effects by binding to specific target gene promoter sequences as homo- or heterodimers and inducing retinoic acid-mediated activation of target gene transcription. RXR/LXRs and RXR/FXR may mediate cholesterol homeostasis, by governing cholesterol transport from peripheral cells, inhibiting cholesterol absorption in the small intestine, and repressing bile acid synthesis through upregulation of ABC1 and repression of CYP7A1 expression. (NCI) ( NCI )]
UMLS (NCI) C0165955
 
Amino Acid, Peptide, or Protein
Receptor

Buy website

Medical Clinic. Optician. Pharmacy. Physician. Travel Agency. Hotel reservation. Child Care. Education. Teachers. Lessons. Tests and Exams. Certification. Shopping Center. Store. Real Estate.
Affordable prices from $100.

 home Dictionaries Armenian-English English-Armenian MeSH Feedback  top
© 2008 -2011 Administrator MEDINDEX.AM