RAMIPRIL
[A prodrug and nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de-esterification into its active form ramiprilat, which inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This abolishes the potent vasoconstrictive actions of angiotensin II and leads to vasodilatation. This agent also causes an increase in bradykinin levels and a decrease in angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. ( NCI )]
UMLS (NCI) C0072973- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [CV800] ACE INHIBITORS
Bicyclo Compounds, Heterocyclic
Bicyclo Compounds, Heterocyclic
Relation/CHD: RAMIPRIL 1.25 MG
RAMIPRIL 10 MG
RAMIPRIL 2.5 MG
RAMIPRIL 5 MG
RAMIPRIL 10 MG
RAMIPRIL 2.5 MG
RAMIPRIL 5 MG
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